Suppr超能文献

食管胃交界癌软脑膜转移癌的姑息治疗方法

Palliative approach to leptomeningeal carcinomatosis in oesophagogastric junction cancer.

作者信息

Cunha Renato, Godinho João, Inácio Mariana, Galriça Neto Isabel

机构信息

Medical Oncology Department, Hospital do Espirito Santo de Évora EPE, Évora, Portugal

Medical Oncology Department, Hospital Beatriz Ângelo, Loures, Portugal.

出版信息

BMJ Case Rep. 2019 Oct 10;12(10):e230114. doi: 10.1136/bcr-2019-230114.

Abstract

Leptomeningeal carcinomatosis (LC) is rare in solid tumours, particularly in gastrointestinal cancers. While other treatment strategies remain undefined, inclusion of palliative care is essential due to its very poor prognosis and variable manifestations. We report a case of oesophagogastric junction adenocarcinoma, previously submitted to surgery and chemotherapy, diagnosed with LC and followed in a palliative care unit. Treatment was comanaged with the oncology team and a palliative approach was decided. In this report, we review the literature and evaluate treatment options, with focus on the importance of palliative care and its potential benefits in patients diagnosed with this rare entity.

摘要

软脑膜癌病(LC)在实体肿瘤中较为罕见,尤其是在胃肠道癌症中。虽然其他治疗策略尚不明确,但鉴于其预后极差且表现多样,纳入姑息治疗至关重要。我们报告一例食管胃交界腺癌患者,此前接受过手术和化疗,诊断为软脑膜癌病,并在姑息治疗病房接受随访。治疗由肿瘤学团队共同管理,并决定采用姑息治疗方法。在本报告中,我们回顾了文献并评估了治疗选择,重点关注姑息治疗的重要性及其对诊断为这种罕见疾病的患者的潜在益处。

相似文献

3
Chemotherapy for Esophageal Adenocarcinoma.食管腺癌的化疗
Methods Mol Biol. 2018;1756:19-34. doi: 10.1007/978-1-4939-7734-5_3.
4
Oesophagogastric junction adenocarcinoma: which therapeutic approach?食管胃结合部腺癌:哪种治疗方法?
Lancet Oncol. 2011 Mar;12(3):296-305. doi: 10.1016/S1470-2045(10)70125-X. Epub 2010 Nov 23.
10
Esophageal and esophagogastric junction cancers, version 1.2015.食管和胃食管交界处癌,第 1.2015 版。
J Natl Compr Canc Netw. 2015 Feb;13(2):194-227. doi: 10.6004/jnccn.2015.0028.

本文引用的文献

3
How we treat patients with leptomeningeal metastases.我们如何治疗软脑膜转移患者。
ESMO Open. 2019 May 21;4(Suppl 2):e000507. doi: 10.1136/esmoopen-2019-000507. eCollection 2019.
6
Leptomeningeal disease: current diagnostic and therapeutic strategies.柔脑膜疾病:当前的诊断与治疗策略
Oncotarget. 2017 Aug 16;8(42):73312-73328. doi: 10.18632/oncotarget.20272. eCollection 2017 Sep 22.
8
Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge.胃癌的软脑膜癌病:一项治疗挑战。
Biomark Insights. 2017 Mar 16;12:1177271917695237. doi: 10.1177/1177271917695237. eCollection 2017.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验