起源于食管胃交界部/胃癌的柔脑膜转移：两例简要报告

Leptomeningeal metastases originated from esophagogastric junction/gastric cancer: A brief report of two cases.

作者信息

Kountourakis Panteleimon, Papamichael Demetris, Haralambous Haris, Michael Michael, Nakos Georgios, Lazaridou Sylvia, Fotiou Eleni, Vassiliou Vassilios, Andreopoulos Demetrios

机构信息

Department of Medical Oncology, BOC Oncology Centre, Nicosia 2006, Cyprus.

Department of Radiology, BOC Oncology Centre, Nicosia 2006, Cyprus.

出版信息

World J Gastrointest Oncol. 2018 Jan 15;10(1):56-61. doi: 10.4251/wjgo.v10.i1.56.

DOI:10.4251/wjgo.v10.i1.56

PMID:29375749

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5767794/

Abstract

Leptomeningeal carcinomatosis is a very rare manifestation in patients diagnosed with esophagogastric junction and gastric cancer. Its prognosis is ominous and therapy outcomes are disappointing. Herein, we present two patients; one initially diagnosed with gastric cancer and leptomeningeal carcinomatosis but no other evidence of metastatic disease and the other one initially diagnosed with esophagogastric junction cancer, who recurred solitary with leptomeningeal seedings several years after the initial diagnosis and treatment. Furthermore, a thorough and short review of the literature is carried out.

摘要

柔脑膜癌病在被诊断为食管胃交界部癌和胃癌的患者中是一种非常罕见的表现。其预后凶险，治疗结果令人失望。在此，我们报告两例患者；一例最初被诊断为胃癌合并柔脑膜癌病，但无其他转移疾病证据，另一例最初被诊断为食管胃交界部癌，在初次诊断和治疗数年之后出现孤立性复发并伴有柔脑膜播散。此外，还对文献进行了全面且简短的回顾。