胃癌的软脑膜癌病：一项治疗挑战。
Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge.
作者信息
Vergoulidou Maria
机构信息
Division of Hematology and Oncology, First Internal Medicine Department, Dietrich-Bonhoeffer-Klinikum, Neubrandenburg, Germany.
出版信息
Biomark Insights. 2017 Mar 16;12:1177271917695237. doi: 10.1177/1177271917695237. eCollection 2017.
Leptomeningeal carcinomatosis (LC) is a rare and mainly secondary site of metastasis in solid tumors. In gastric cancer (GC), it is associated with a devastating prognosis, lacking an efficient and standardized treatment approach. We report a case of primary manifestation of LC due to metastatic GC with rapid deterioration and refractory course to conventional and intrathecal chemotherapy. We review the literature and discuss the therapeutic challenges.
柔脑膜癌病（LC）是实体瘤中一种罕见的主要转移部位。在胃癌（GC）中，它与毁灭性的预后相关，缺乏有效的标准化治疗方法。我们报告了一例因转移性GC导致LC的首发表现，病情迅速恶化，对传统化疗和鞘内化疗均呈难治性病程。我们回顾了文献并讨论了治疗挑战。
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