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用于最大限度降低术中神经损伤风险的神经体内短波近红外荧光成像。

Shortwave infrared fluorescence in vivo imaging of nerves for minimizing the risk of intraoperative nerve injury.

机构信息

Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Department of Orthopedic Sports Medicine, Huashan Hospital, Fudan University, Shanghai, China.

出版信息

Nanoscale. 2019 Nov 14;11(42):19736-19741. doi: 10.1039/c9nr06066a. Epub 2019 Oct 18.

Abstract

Here, we present a novel nerve specific imaging agent for preventing intraoperative nerve injuries based on SWIR QD-based in vivo imaging, which not only provides real-time and long-time SWIR images to intraoperatively identify nerves but can also markedly minimize the risk of iatrogenic nerve injuries during surgeries.

摘要

在这里,我们提出了一种基于近红外二区量子点(SWIR QD)体内成像的新型神经特异性成像剂,用于预防术中神经损伤,它不仅可以提供实时和长时间的近红外二区 SWIR 图像,以便术中识别神经,还可以显著降低手术过程中医源性神经损伤的风险。

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