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[免疫与肿瘤。恶性肿瘤患者中E玫瑰花结形成淋巴细胞的行为]

[Immunity and neoplasms. Behavior of E rosette-forming lymphocytes in patients with malignant neoplasms].

作者信息

Dolci C, Pistone M A, Testa D, Grosso B, Resegotti L

出版信息

Arch Sci Med (Torino). 1979 Apr-Jun;136(2):279-84.

PMID:316319
Abstract

The per cent and absolute figures of E rosette forming lymphocytes have been evaluated in the blood of normal subject and of patients with non-neoplastic diseases and with epithelial and lymphoreticular tumours. The percentage of rosetting lymphocytes was not affected by non-neoplastic diseases, whilst it was by tumours, especially by lymphoreticular ones. However differences were not statistically significant in view of the large dispersion of values. Absolute counts of rosetting lymphocytes displayed lesser variations. These findings are better explained by Schwartz's concept of immunoregulation than by Burnet's theory of immunosurveillance.

摘要

已对正常受试者、非肿瘤性疾病患者、上皮肿瘤患者和淋巴网状肿瘤患者血液中的E玫瑰花结形成淋巴细胞的百分比及绝对值进行了评估。玫瑰花结形成淋巴细胞的百分比不受非肿瘤性疾病影响,而受肿瘤影响,尤其是淋巴网状肿瘤。然而,鉴于数值的较大离散度,差异无统计学意义。玫瑰花结形成淋巴细胞的绝对计数变化较小。这些发现用施瓦茨的免疫调节概念比用伯内特的免疫监视理论能得到更好的解释。

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