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在螺旋断层放疗全头皮照射中通过虚拟 bolus 提高对摆位误差的鲁棒性。

Improvement of the robustness to set up error by a virtual bolus in total scalp irradiation with Helical TomoTherapy.

作者信息

Takenaka Ryosuke, Haga Akihiro, Nawa Kanabu, Hideomi Yamashita, Nakagawa Keiichi

机构信息

Department of Radiology, University of Tokyo Hospital, 7-3-1Bunkyo-ku, HongoTokyo, 113-8655, Japan.

Department of Medical Image Informatics, Tokushima University, Tokushima, Japan.

出版信息

Radiol Phys Technol. 2019 Dec;12(4):433-437. doi: 10.1007/s12194-019-00539-1. Epub 2019 Oct 23.

Abstract

Intensity-modulated radiation therapy has recently been used for total scalp irradiation. In inverse planning, the treatment planning system increases the fluence of tangential beam near the skin surface to counter the build-up region. Consequently, the dose to the skin surface increases even with small setup errors. Replacing the electron density of the surrounding air of some thickness with a virtual bolus during optimization could suppress the extremely high fluence near the skin. We confirmed the usefulness of a virtual bolus in total scalp irradiation. For each patient, two beams were planned, one with and the other without a virtual bolus. The dose distribution was calculated using computed tomography images that were shifted to simulate setup errors. The hot spot dose was suppressed in the plans using a virtual bolus. In conclusion, using a virtual bolus improved the robustness to setup errors.

摘要

调强放射治疗最近已用于全头皮照射。在逆向计划中,治疗计划系统会增加皮肤表面附近切线束的注量,以抵消剂量建成区。因此,即使设置误差很小,皮肤表面的剂量也会增加。在优化过程中用虚拟组织填充物替代一定厚度周围空气的电子密度,可以抑制皮肤附近极高的注量。我们证实了虚拟组织填充物在全头皮照射中的有用性。对于每位患者,设计了两个计划,一个使用虚拟组织填充物,另一个不使用。使用移位的计算机断层扫描图像来模拟设置误差,计算剂量分布。使用虚拟组织填充物的计划中热点剂量得到了抑制。总之,使用虚拟组织填充物提高了对设置误差的稳健性。

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