University of Oklahoma (OU) College of Arts and Sciences, Norman, OK.
OU Center on the Ethics of Indigenous Genomic Research, Norman, OK.
Am J Phys Anthropol. 2020 Feb;171(2):177-181. doi: 10.1002/ajpa.23943. Epub 2019 Oct 23.
The metabolome is a system of small biomolecules (metabolites) and a direct result of human bioculture. Consequently, metabolomics is well poised to impact anthropological and biomedical research for the foreseeable future. Overall, we provide a perspective on the ethical, legal, and social implications (ELSI) of metabolomics, which we argue are often more alarming than those of genomics. Given the current mechanisms to fund research, ELSI beyond human DNA is stifled and in need of considerable attention.
代谢组是小分子生物分子（代谢物）的系统，也是人类生物培养的直接结果。因此，代谢组学有望在可预见的未来对人类学和生物医学研究产生影响。总的来说，我们提供了一个关于代谢组学的伦理、法律和社会影响（ELSI）的观点，我们认为这些影响通常比基因组学的更令人担忧。考虑到当前的研究资金机制，超越人类 DNA 的 ELSI 受到了抑制，需要引起相当的关注。
