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老年结直肠癌患者临终关怀模式和费用:对美国和加拿大的描述性研究。

Patterns of Care and Costs for Older Patients With Colorectal Cancer at the End of Life: Descriptive Study of the United States and Canada.

机构信息

Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.

Toronto Health Economics and Technology Assessment Collaborative, Toronto, Ontario, Canada.

出版信息

JCO Oncol Pract. 2020 Jan;16(1):e1-e18. doi: 10.1200/JOP.19.00061. Epub 2019 Oct 24.

Abstract

PURPOSE

End-of-life (EOL) cancer care is costly, with challenges regarding intensity and place of care. We described EOL care and costs for patients with colorectal cancer (CRC) in the United States and the province of Ontario, Canada, to inform better care delivery.

METHODS

Patients diagnosed with CRC from 2007 to 2013, who died of any cancer from 2007 to 2013 at age ≥ 66 years, were selected from the US SEER cancer registries linked to Medicare claims (n = 16,565) and the Ontario Cancer Registry linked to administrative health data (n = 6,587). We estimated total and resource-specific costs (2015 US dollars) from public payer perspectives over the last 360 days of life by 30-day periods, by stage at diagnosis (0-II, III, IV).

RESULTS

In all months, especially 30 days before death, higher percentages of SEER-Medicare than Ontario patients received chemotherapy (15.7% 8.0%), and imaging tests (39.4% 31.1%). A higher percentage of Ontario patients were hospitalized (62.5% 51.0%), but 43.2% of hospitalized SEER-Medicare patients had intensive care unit (ICU) admissions versus 17.9% of hospitalized Ontario patients. Cost differences between cohorts were greater for patients with stage IV disease. In the last 30 days, mean total costs for patients with stage IV disease were $15,881 (SEER-Medicare) and $12,034 (Ontario) versus $19,354 and $17,312 for stage 0-II. Hospitalization costs were higher for SEER-Medicare patients ($11,180 $9,434), with lower daily hospital costs in Ontario ($1,067 $2,004).

CONCLUSION

These findings suggest opportunities for reducing chemotherapy and ICU use in the United States and hospitalizations in Ontario.

摘要

目的

生命末期(EOL)癌症护理费用高昂,在护理强度和地点方面存在挑战。我们描述了美国和加拿大安大略省的结直肠癌(CRC)患者的 EOL 护理和费用,以提供更好的护理服务。

方法

从美国 SEER 癌症登记处和医疗保险索赔中选择了 2007 年至 2013 年间诊断为 CRC 的患者(n=16565),以及从安大略癌症登记处和行政健康数据中选择了 2007 年至 2013 年期间年龄≥66 岁死于任何癌症的患者(n=6587)。我们从公共支付者的角度,按诊断时的分期(0-II、III、IV),通过 30 天的时间段,估算了生命最后 360 天内的总资源特异性成本(2015 年美元)。

结果

在所有月份,尤其是死亡前 30 天,SEER-医疗保险患者接受化疗(15.7%对 8.0%)和影像学检查(39.4%对 31.1%)的比例明显高于安大略患者。更多的安大略患者住院(62.5%对 51.0%),但住院的 SEER-医疗保险患者中有 43.2%住进了重症监护病房(ICU),而住院的安大略患者中只有 17.9%。疾病分期为 IV 期的患者之间的成本差异更大。在最后 30 天,疾病分期为 IV 期的患者的总费用平均为 15881 美元(SEER-医疗保险)和 12034 美元(安大略),而疾病分期为 0-II 期的患者则为 19354 美元和 17312 美元。SEER-医疗保险患者的住院费用较高(11180 美元对 9434 美元),而安大略的日住院费用较低(1067 美元对 2004 美元)。

结论

这些发现表明,美国可以减少化疗和 ICU 的使用,而安大略可以减少住院治疗。

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本文引用的文献

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Cancer statistics, 2019.癌症统计数据,2019 年。
CA Cancer J Clin. 2019 Jan;69(1):7-34. doi: 10.3322/caac.21551. Epub 2019 Jan 8.
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The Real Cost of the US Health Care System.美国医疗保健系统的实际成本。
JAMA. 2018 Mar 13;319(10):983-985. doi: 10.1001/jama.2018.1151.
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Canada's universal health-care system: achieving its potential.加拿大的全民医疗保健系统:发挥其潜力。
Lancet. 2018 Apr 28;391(10131):1718-1735. doi: 10.1016/S0140-6736(18)30181-8. Epub 2018 Feb 23.
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A National Palliative Care Strategy for Canada.加拿大国家姑息治疗战略。
J Palliat Med. 2018 Jan;21(S1):S63-S75. doi: 10.1089/jpm.2017.0431.

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