Faculty of Medicine, University of Porto, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal.
Department of Neurosurgery, Centro Hospitalar Universitário de São João, Porto, Portugal.
Acta Neurochir (Wien). 2019 Dec;161(12):2415-2420. doi: 10.1007/s00701-019-04079-w. Epub 2019 Oct 24.
A variety of surgical techniques can be used to achieve lumbar spinal fusion for management of degenerative conditions. Transforaminal lumbar interbody fusion (TLIF) is the most popular technique; however, midline lumbar interbody fusion (MIDLIF) is a valid alternative to the more traditional pedicle screw trajectory with potential advantages. The aim of this study is to evaluate the clinical outcomes from a cohort of patients submitted to MIDLIF in a single hospital during the surgical team's initial learning period.
The first 30 consecutive patients who underwent single- or two-level MIDLIF surgery for lumbar degenerative disease were included in this retrospective study. Patients' demographics, surgical data, length of hospitalisation, and perioperative complications were analysed. Preoperative and postoperative radiographic parameters were obtained. Validated questionnaires, Core Outcome Measure Index for the back, Euro-QoL 5-Dimensional Questionnaire, and Oswestry Disability Index, were used for clinical assessment.
Mean surgery time was 278.53 ± 82.16 min and mean hospitalisation time was 6.17 ± 3.51 days. Six patients experienced complications, four of which being dural tears with no consequences, and two required reoperations during the mean follow-up of 25.23 ± 9.74 months. Preoperative and postoperative radiological parameters did not demonstrate significant differences. All clinical parameters significantly improved after surgery (p < 0.001). A complexity score was developed to more accurately compare the different procedures, and it strongly correlated with surgery duration (r = 0.719, p < 0.001). Furthermore, a moderate correlation was found between a developed Duration Index and the patient's order number (r = - 0.539, p = 0.002).
In our initial experience, MIDLIF showed to be effective in significantly improving the patients' functional status, pain scores, and quality of life. The technique seems safe, with an acceptably low complication rate. Hence, MIDLIF can be considered as a promising alternative to more traditional TLIF and PLIF techniques even at the beginning of the learning curve.
多种手术技术可用于治疗退行性疾病的腰椎融合。经椎间孔腰椎体间融合术(TLIF)是最常用的技术;然而,中线腰椎体间融合术(MIDLIF)是一种替代更传统的椎弓根螺钉轨迹的有效方法,具有潜在优势。本研究旨在评估一组在手术团队的初始学习期间在一家医院接受 MIDLIF 治疗的患者的临床结果。
回顾性分析了 30 例连续接受单节段或双节段 MIDLIF 手术治疗腰椎退行性疾病的患者。分析了患者的人口统计学、手术数据、住院时间和围手术期并发症。获得了术前和术后影像学参数。使用经过验证的问卷,即背部核心结局测量指数、欧洲五维健康量表和 Oswestry 残疾指数,进行临床评估。
平均手术时间为 278.53 ± 82.16 分钟,平均住院时间为 6.17 ± 3.51 天。6 例患者发生并发症,其中 4 例为硬脊膜撕裂但无后果,2 例在平均 25.23 ± 9.74 个月的随访中需要再次手术。术前和术后影像学参数无显著差异。所有临床参数在手术后均显著改善(p < 0.001)。开发了一个复杂性评分来更准确地比较不同的手术,它与手术时间强烈相关(r = 0.719,p < 0.001)。此外,还发现开发的持续时间指数与患者的序号之间存在中度相关性(r = -0.539,p = 0.002)。
在我们的初步经验中,MIDLIF 显示出在显著改善患者的功能状态、疼痛评分和生活质量方面的有效性。该技术似乎是安全的,并发症发生率可接受。因此,即使在学习曲线的早期,MIDLIF 也可以被视为一种有前途的替代传统 TLIF 和 PLIF 技术的方法。