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后路经椎间孔腰椎椎体间融合术(MIDLIF)能否预防早期影像学邻近节段退变?L4/5 皮质骨轨迹螺钉与传统椎弓根螺钉固定的 MIDLIF 至少 3 年随访的比较研究。

May the midline lumbar interbody fusion (MIDLIF) prevent the early radiographic adjacent segment degeneration? A minimum 3-year follow-up comparative study of MIDLIF in L4/5 with cortical bone trajectory screw versus traditional pedicle screw fixation.

机构信息

Department of Orthopedics, Beijing Chao-Yang Hospital, Capital Medical University, GongTiNanLu 8#, Chao-Yang District, Beijing, 100020, China.

出版信息

BMC Musculoskelet Disord. 2022 May 20;23(1):480. doi: 10.1186/s12891-022-05363-0.

Abstract

STUDY DESIGN

Retrospective cohort study.

OBJECTIVE

To compare the early radiographic adjacent segment degeneration (R-ASD) and regional lumbar sagittal alignment after midline lumbar interbody fusion (MIDLIF) with cortical bone trajectory (CBT) screw fixation (CBT-MIDLIF) and posterior lumbar interbody fusion (PLIF) with the traditional pedicle screw fixation (PS-PLIF) during long-term follow-up.

METHODS

All patients who underwent CBT-MIDLIF or PS-PLIF were identified by a retrospective consecutive case review. Radiographic parameters in cephalad adjacent segment (L3/4), including intervertebral space height (ISH), foraminal height (FH), foraminal width (FW), range of motion were assessed. Lumbar lordosis (LL), sacral slope (SS), L4-L5 Cobb angle, Cobb angle of the intervertebral space at L4-L5, and height of the anterior and posterior edges of the intervertebral space at L4-L5, were measured and compared on preoperative, postoperative, and 3-year follow-up radiographic evaluation.

RESULTS

Seventy-four patients underwent CBT-MIDLIF (CBT-MIDLIF group) and 114 patients underwent conventional PS-PLIF (PS-PLIF group). ISH, FH and FW were significantly smaller at 6-month follow-up than before operation with PS-PLIF (p < 0.001) but showed no significant changes with CBT-MIDLIF (p > 0.05). At the last follow-up, the changes in cephalad R-ASD parameters were more remarkable after PS-PLIF than after CBT-MIDLIF (p < 0.01). LL and SS were significant larger at the last follow-up than before operation in both groups (p < 0.001). Regarding long-term outcomes, the symptoms caused by degenerative spinal disorders significantly improved in both groups (p < 0.01).

CONCLUSION

CBT-MIDLIF had less radiographic degeneration in the adjacent segment than PS-PLIF at 3-year follow-up. The lumbar sagittal alignment could be improved significantly and the surgical outcomes were satisfactory after either CBT-MIDLIF or PS-PLIF.

摘要

研究设计

回顾性队列研究。

目的

比较经皮皮质骨轨迹(CBT)螺钉固定的中线腰椎椎间融合术(MIDLIF)与传统经皮椎弓根螺钉固定后路腰椎椎间融合术(PS-PLIF)治疗后,在长期随访中对邻近节段(R-ASD)的早期放射学进展和区域腰椎矢状位排列的影响。

方法

通过回顾性连续病例回顾,确定接受 CBT-MIDLIF 或 PS-PLIF 的所有患者。评估头侧邻近节段(L3/4)的椎间隙高度(ISH)、椎间孔高度(FH)、椎间孔宽度(FW)和活动度等影像学参数。测量并比较术前、术后和 3 年随访时腰椎前凸角(LL)、骶骨倾斜角(SS)、L4-L5 Cobb 角、L4-L5 节段椎间隙 Cobb 角以及 L4-L5 节段椎间隙前缘和后缘高度。

结果

74 例患者接受 CBT-MIDLIF(CBT-MIDLIF 组),114 例患者接受传统 PS-PLIF(PS-PLIF 组)。与 CBT-MIDLIF 相比,PS-PLIF 术后 6 个月 ISH、FH 和 FW 明显减小(p<0.001),但 CBT-MIDLIF 无明显变化(p>0.05)。末次随访时,PS-PLIF 后相邻节段 R-ASD 参数的变化比 CBT-MIDLIF 更显著(p<0.01)。两组末次随访时 LL 和 SS 均明显大于术前(p<0.001)。长期随访结果显示,两组退行性脊柱疾病引起的症状均明显改善(p<0.01)。

结论

在 3 年随访时,CBT-MIDLIF 与 PS-PLIF 相比,邻近节段的放射学退变较少。CBT-MIDLIF 或 PS-PLIF 均可显著改善腰椎矢状位排列,手术效果满意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce01/9121621/07467c4202f1/12891_2022_5363_Fig1_HTML.jpg

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