高频振荡通气治疗新生儿胎粪吸入综合征的疗效
Effectiveness of high-frequency oscillatory ventilation for the treatment of neonatal meconium aspiration syndrome.
作者信息
Hao Li-Xia, Wang Fei
机构信息
Department of Neonatology.
Department of Ophthalmology, Yan'an University Affiliated Hospital, Yan'an, China.
出版信息
Medicine (Baltimore). 2019 Oct;98(43):e17622. doi: 10.1097/MD.0000000000017622.
BACKGROUND
The purpose of this study is to raise nonjudgmental awareness and attention to current experience of high-frequency oscillatory ventilation (HFOV) for the treatment of neonatal meconium aspiration syndrome (NMAS).
METHODS
We will comprehensively search literature from the databases of Cochrane Library, PubMed, Embase, Web of Science, WorldSciNet, PsycINFO, Allied and Complementary Medicine Database, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure from inception until July 1, 2019 without language limitation. We will also handle searching the bibliographies of all relevant studies found for unpublished literatures. Statistical analysis will be conducted using RevMan 5.3 software.
RESULTS
The outcomes include function inhaled oxygen concentration, oxygenation index, arterial oxygen tension/alveolar arterial oxygen tension, partial pressure of oxygen, partial pressure of carbon dioxide, transcutaneous arterial oxygen saturation, duration of hospitalization, and adverse events.
CONCLUSION
This study will provide an exhaustive view of HFOV for treating infants with NMAS.
PROSPERO REGISTRATION NUMBER
PROSPERO CRD42019140520.
背景
本研究旨在提高对高频振荡通气（HFOV）治疗新生儿胎粪吸入综合征（NMAS）当前经验的无偏见认识和关注。
方法
我们将全面检索Cochrane图书馆、PubMed、Embase、科学网、WorldSciNet、PsycINFO、补充与替代医学数据库、中国生物医学文献数据库和中国知网等数据库自创建至2019年7月1日的文献，无语言限制。我们还将检索所有相关研究的参考文献以查找未发表的文献。将使用RevMan 5.3软件进行统计分析。
结果
结果包括功能吸入氧浓度、氧合指数、动脉血氧分压/肺泡动脉血氧分压差、氧分压、二氧化碳分压、经皮动脉血氧饱和度、住院时间和不良事件。
结论
本研究将全面展示HFOV治疗NMAS婴儿的情况。
PROSPERO注册号：PROSPERO CRD42019140520。
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