Panezai Muhammad Ajmal, Ahmed Sana, Colbert Gates B
Department of Internal Medicine, Baylor University Medical Center at DallasDallasTexas.
Division of Nephrology, Department of Internal Medicine, Baylor University Medical Center at DallasDallasTexas.
Proc (Bayl Univ Med Cent). 2019 Jul 15;32(4):624-626. doi: 10.1080/08998280.2019.1624092. eCollection 2019 Oct.
Sagliker syndrome (SS), also known as an "uglifying human face syndrome," is one of the severe manifestations of chronic kidney disease in patients with uncontrolled secondary hyperparathyroidism. Patients with SS develop short stature, maxillary and mandibular bone overgrowth, nasal bone and cartilage destruction, widely spaced teeth with anterior positioning, soft tissue tumors in the oral cavity, auditory loss, and neurological and psychological features. SS can possibly be prevented with proper treatment of secondary hyperparathyroidism using disease-modifying medication and surgical therapies. We report a case of SS in a patient in the USA with end-stage renal disease achieving adequate hemodialysis.
萨利克综合征（SS），也被称为“毁容性人面综合征”，是继发性甲状旁腺功能亢进未得到控制的慢性肾病患者的严重表现之一。患有萨利克综合征的患者会出现身材矮小、上颌和下颌骨过度生长、鼻骨和软骨破坏、牙齿间距宽且向前移位、口腔软组织肿瘤、听力丧失以及神经和心理特征。通过使用改善病情的药物和手术疗法对继发性甲状旁腺功能亢进进行适当治疗，有可能预防萨利克综合征。我们报告了美国一名患有终末期肾病且血液透析充分的患者发生萨利克综合征的病例。
