Karimi Saeed, Pahlevani Pouyan
Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Ophthalmology, Torfeh Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Ophthalmic Vis Res. 2019 Jul 18;14(3):376-381. doi: 10.18502/jovr.v14i3.4794. eCollection 2019 Jul-Sep.
To report an extremely rare case of tapioca melanoma of the iris in an Iranian patient.
A 50-year-old male patient presented with ocular pain and redness in the right eye for two weeks. The visual acuity was 7/10 and the intraocular pressure (IOP) was 30 mmHg. A lobulated amelanotic vascularized and nodular (tapioca-like) iris mass with a 180 extent was seen in the right eye. Incisional biopsy of the mass revealed atypical mixed type (epithelioid and spindle cell) melanoma. Brachytherapy with the ruthenium-106 plaque resulted in complete regression of the tumor.
Tapioca melanoma of the iris should be considered in the differential diagnosis of patients presenting with nodular vascularized amelanotic iris mass and elevated IOP. Brachytherapy with ruthenium-106 seems to be an effective treatment for tapioca melanoma of the iris.
报告一例伊朗患者发生的极为罕见的虹膜木薯样黑色素瘤病例。
一名50岁男性患者右眼眼痛、眼红两周。视力为7/10，眼压（IOP）为30 mmHg。右眼可见一个呈分叶状、无色素、血管化的结节状（木薯样）虹膜肿物，范围达180°。肿物切取活检显示为非典型混合型（上皮样和梭形细胞）黑色素瘤。钌-106敷贴近距离放射治疗使肿瘤完全消退。
对于出现结节状、血管化、无色素虹膜肿物及眼压升高的患者，鉴别诊断时应考虑虹膜木薯样黑色素瘤。钌-106近距离放射治疗似乎是虹膜木薯样黑色素瘤的一种有效治疗方法。
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