Bogolyubova A V
Center for Genetics and Life Sciences, Educational Center "Sirius," Educational Fund "Talent and Success," Sochi, 354340 Russia.
apollinariya.bogolyubova@gmail. com.
Mol Biol (Mosk). 2019 Sep-Oct;53(5):871-880. doi: 10.1134/S0026898419050033.
Numerous studies on the nature of neoplastic growth have demonstrated that oncogenic viruses maybe one of the factors causing cancer. According to various estimates, 10-20% of all human cancers are caused by viruses. For example, the Epstein-Barr virus (EBV), hepatitis B and C viruses, human papillomavirus (HPV), human T-lymphotropic virus type 1 (HTLV-1), human herpesvirus type 8 (HHV-8), and Merkel cell polyomavirus were implicated in initiating tumors. At the same time, the long period between viral infection and the manifestation of cancer significantly complicates the search for a causal relationship between the presence of a virus in the human organism and the malignant transformation. For this reason, the role of certain viruses in the initiation of neoplastic processes in humans remains an unresolved issue.
众多关于肿瘤生长本质的研究表明，致癌病毒可能是导致癌症的因素之一。据各种估计，所有人类癌症中有10% - 20%是由病毒引起的。例如，爱泼斯坦 - 巴尔病毒（EBV）、乙型和丙型肝炎病毒、人乳头瘤病毒（HPV）、1型人类嗜T淋巴细胞病毒（HTLV - 1）、8型人类疱疹病毒（HHV - 8）和默克尔细胞多瘤病毒都与肿瘤的引发有关。同时，病毒感染与癌症显现之间的长时间间隔显著增加了探寻人类机体中病毒存在与恶性转化之间因果关系的难度。因此，某些病毒在人类肿瘤形成过程中的作用仍是一个未解决的问题。
