采用理论方法预测大学生非医疗目的使用处方药物——生存分析。
Using a theoretical approach to predict college students' non-medical use of prescription drugs - a survival analysis.
机构信息
Department of Clinical and Administrative Pharmacy, College of Pharmacy, University of Georgia, Athens, Georgia, USA.
Statistics Department, University of Georgia, Athens, Georgia, USA.
出版信息
J Am Coll Health. 2021 Jul;69(5):470-477. doi: 10.1080/07448481.2019.1680556. Epub 2019 Oct 29.
This study assesses students' non-medical use of prescription drugs (NMUPD) from college entrance to graduation, and examines factors that predict NMUPD. : The study was conducted between May 2011 and September 2015 with 338 students. Longitudinal cohort study design was used to examine NMUPD across time, and NMUPD-related attitudes and subjective norms. Five yearly interviews were conducted to collect data. Cox proportional hazards regression analysis was used to examine time to NMUPD. : Thirty-five percent of study participants reported NMUPD; the majority of those initiated non-medical use before their third year in college. Analyses indicated that more positive attitudes towards NMUPD (HR = 1.73, < 0.001), increased subjective norms regarding NMUPD (HR = 1.01, < 0.01), and gender (male) (HR= 1.89, < 0.001) were significantly associated with sooner NMUPD. : Findings suggest that NMUPD prevention efforts that target mutable factors such as attitudes and subjective norms should be implemented early during students' college careers.
本研究评估了学生从大学入学到毕业期间的非医疗性处方药物使用（NMUPD）情况，并探讨了预测 NMUPD 的因素。该研究于 2011 年 5 月至 2015 年 9 月期间对 338 名学生进行了纵向队列研究设计，以考察 NMUPD 随时间的变化情况，以及与 NMUPD 相关的态度和主观规范。研究共进行了五次年度访谈以收集数据。采用 Cox 比例风险回归分析来检验 NMUPD 的时间。研究参与者中有 35%报告了 NMUPD；其中大多数人在大学第三年之前就开始了非医疗性使用。分析表明，对 NMUPD 的态度越积极（HR = 1.73，<0.001），对 NMUPD 的主观规范越高（HR = 1.01，<0.01），以及性别（男性）（HR= 1.89，<0.001），与 NMUPD 的发生时间呈显著正相关。研究结果表明，应该在学生的大学生涯早期就针对态度和主观规范等可改变因素开展 NMUPD 预防工作。
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