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大学生非医疗目的使用非处方药与非医疗目的使用处方药显著相关。

Nonmedical use of over-the-counter medications is significantly associated with nonmedical use of prescription drugs among university students.

作者信息

Le Vi T, Norris Turner Abigail, McDaniel Anne, Hale Kenneth M, Athas Christina, Kwiek Nicole C

机构信息

a College of Public Health , The Ohio State University , Columbus , Ohio , USA.

b Division of Infectious Diseases, College of Medicine , The Ohio State University , Columbus , Ohio , USA.

出版信息

J Am Coll Health. 2018 Jan;66(1):1-8. doi: 10.1080/07448481.2017.1356312. Epub 2017 Sep 15.

DOI:10.1080/07448481.2017.1356312
PMID:28812451
Abstract

OBJECTIVE

To examine the association between nonmedical use of over-the-counter medications (NMUOTC) and nonmedical use of prescription drugs (NMUPD).

PARTICIPANTS

University students surveyed on NMUOTC and NMUPD between August and December 2011 (N = 939).

METHODS

Cross-sectional data analysis of online survey.

RESULTS

The majority of respondents were women, undergraduate, Caucasian, and not affiliated with Greek life. NMUPD and NMUOTC were reported by 21.4% and 11.2% of students, respectively. NMUOTC was significantly associated with NMUPD in unadjusted analyses and after adjustment for gender, age, race/ethnicity, and Greek membership (odds ratio: 3.37, 95% confidence interval: 2.17, 5.23). Secondary analyses showed a relationship between over-the-counter (OTC) cough medication misuse and NMUPD, OTC stimulant misuse and prescription stimulant misuse, and OTC sleep aid misuse with prescription depressant misuse.

CONCLUSIONS

Results suggest the importance of both measuring the prevalence of OTC misuse and incorporating its misuse into assessments of polydrug use in the university population.

摘要

目的

探讨非医疗目的使用非处方药物(NMUOTC)与非医疗目的使用处方药(NMUPD)之间的关联。

参与者

2011年8月至12月期间接受非医疗目的使用非处方药物和非医疗目的使用处方药调查的大学生(N = 939)。

方法

对在线调查进行横断面数据分析。

结果

大多数受访者为女性、本科生、白种人,且未加入兄弟会或姐妹会。分别有21.4%和11.2%的学生报告有非医疗目的使用处方药和非医疗目的使用非处方药物的情况。在未经调整的分析以及调整性别、年龄、种族/族裔和是否加入兄弟会或姐妹会后,非医疗目的使用非处方药物与非医疗目的使用处方药显著相关(比值比:3.37,95%置信区间:2.17,5.23)。二次分析显示,非处方止咳药滥用与非医疗目的使用处方药、非处方兴奋剂滥用与处方兴奋剂滥用以及非处方助眠药滥用与处方镇静剂滥用之间存在关联。

结论

结果表明,测量非处方药物滥用的患病率并将其纳入对大学生多药使用的评估中具有重要意义。

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