化疗联合放疗后非己烯雌酚暴露的透明细胞阴道癌的前路盆腔廓清术
Anterior Pelvic Exenteration for Chemo-irradiated Non-diethylstilbestrol Exposed Clear Cell Vaginal Cancer.
机构信息
"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
"I. Cantacuzino" Clinical Hospital, Bucharest, Romania.
出版信息
In Vivo. 2019 Nov-Dec;33(6):2299-2302. doi: 10.21873/invivo.11737.
BACKGROUND/AIM: Clear cell vaginal adeno-carcinomas are rare tumors occurring in women which are usually treated by chemo radiotherapy with good outcomes. However, in certain cases, this treatment is not associated with complete response and a further surgery is needed.
CASE REPORT
We present the case of a 38-year-old patient diagnosed with stage IVA clear cell vaginal cancer who had been previously submitted to radio chemotherapy and in whom the lesion persisted after the oncological treatment; therefore, the patient was proposed for surgery with curative intent. The tumor was resected by performing an anterior pelvic exenteration with good outcomes, the patient being discharged in the seventh postoperative day. At one-year follow-up the patient remains free of recurrent disease.
CONCLUSION
Pelvic exenteration with curative intent might be the option of choice for persistent locally advanced clear cell vaginal cancer.
背景/目的：透明细胞阴道腺肉瘤是一种罕见的发生于女性的肿瘤，通常采用化疗和放疗进行治疗，预后良好。然而，在某些情况下，这种治疗并不能完全缓解病情，需要进一步手术。
病例报告
我们报告了一例 38 岁的 IVA 期透明细胞阴道癌患者，该患者曾接受过放化疗，在肿瘤治疗后仍有病变存在；因此，该患者被建议进行有治愈意图的手术。通过实施前盆腔切除术切除了肿瘤，术后患者恢复良好，在第七天出院。在一年的随访中，患者无疾病复发。
结论
对于局部晚期透明细胞阴道癌的持续性病变，有治愈意图的盆腔切除术可能是首选方案。
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