López-Torres López Jesús, Blázquez Abellán Gemma, López-Torres Hidalgo María Rosa, Milián García Rosa María, López Martínez Consuelo
Departamento de Ciencias Médicas. Facultad de Farmacia de Albacete. Universidad de Castilla-La Mancha. Albacete. España.
Farmacia Comunitaria. Albacete. España.
Rev Esp Salud Publica. 2019 Oct 30;93:e201910080.
Medication satisfaction is a patientcentered measure that helps predict the continuity of treatment, correct use and therapeutic compliance. The objective has been to evaluate the satisfaction with the treatment (ST) of subjects with arterial hypertension (HT) and find out if the type of treatment, the state of health and the personal characteristics are related to the satisfaction.
Observational cross-sectional study conducted in the community pharmacy field. A total of 484 users of antihypertensive medication were evaluated (response rate: 81.6%). The ST was evaluated through the Treatment Satisfaction with Medicines. In the statistical analysis, means comparison and correlation tests were used to verify the existence of associations between the ST level and the different variables, considering a significance level of p<0.05. Likewise, a multiple linear regression model was constructed to identify the associated variables avoiding possible confounding factors.
In a range of 0-100 the mean ST value was 79.9 (SD=12.9, 95% CI=78.8-81.0). A weak correlation was observed between perceived health score and ST (r=0.145, p=0.001). ST was higher in subjects with controlled BP (82.1 ±12.1 SD vs 77.5 ±13.3 SD, p<0.001), in treated subjects over 5 years (83.5 ± 12.8 SD vs 78.5 ±12.6 SD; p<0.001), in subjects without adverse effects (82.5 ±11.6 SD vs 68.7 ±11.9 SD; p<0.001) and in lower social classes (81.2 ±12.8 SD vs 78.5 ±12.8 SD, p=0.02). It was lower in the non-compliers with the treatment (73.2 ±12.9 vs 82.1 ±12.1, p<0.001).
The ST level is acceptable, despite insufficient BP control and the high rate of noncompliance. Satisfaction is conditioned both by effectiveness and by therapeutic adherence, although health status, treatment and personal characteristics also intervene.
药物满意度是以患者为中心的一项指标,有助于预测治疗的连续性、正确用药情况及治疗依从性。本研究旨在评估动脉高血压(HT)患者对治疗的满意度(ST),并探究治疗类型、健康状况及个人特征是否与满意度相关。
在社区药房领域开展观察性横断面研究。共评估了484名抗高血压药物使用者(应答率:81.6%)。通过药物治疗满意度量表评估ST。在统计分析中,采用均值比较和相关性检验来验证ST水平与不同变量之间是否存在关联,显著性水平设定为p<0.05。同样,构建多元线性回归模型以识别相关变量,避免可能的混杂因素。
在0至100的范围内,ST的均值为79.9(标准差=12.9,95%置信区间=78.8-81.0)。在感知健康评分与ST之间观察到弱相关性(r=0.145,p=0.001)。血压得到控制的患者的ST更高(82.1±12.1标准差 vs 77.5±13.3标准差,p<0.001),接受治疗超过5年的患者的ST更高(83.5±12.8标准差 vs 78.5±12.6标准差;p<0.001),无不良反应患者的ST更高(82.5±11.6标准差 vs 68.7±11.9标准差;p<0.001),社会阶层较低的患者的ST更高(81.2±12.8标准差 vs 78.5±12.8标准差,p=0.02)。治疗不依从者的ST较低(73.2±12.9 vs 82.1±第十二点一,p<0.001)。
尽管血压控制不足且不依从率较高,但ST水平是可以接受的。满意度既受疗效影响,也受治疗依从性影响,尽管健康状况、治疗及个人特征也有干预作用。