Askari Neda, Momtaz Hassan, Tajbakhsh Elahe
Ph.D Student of Microbiology, Department of Microbiology, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.
Department of Microbiology, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.
AIMS Microbiol. 2019 Sep 23;5(3):272-284. doi: 10.3934/microbiol.2019.3.272. eCollection 2019.
genus belongs to a group of Gram-negative coccobacillus. These bacteria are isolated from human and animal origins. Antimicrobial agents play a vital role in treating infectious diseases in both humans and animals, and in this regard is defined as an organism of low virulence. The current study aimed to evaluate antibiotic resistance properties and virulence factor genes in strains isolated from raw animal meat samples. Fresh meat samples from 124 sheep, 162 goat, and 95 camels were randomly collected from Isfahan and Shahrekord cities in Iran. Most strains isolated from sheep meat samples represented (82.35%), (78.43%), (78.43%) and Integron Class I (96.07%) genes. Moreover, more than 50% of strains isolated from sheep samples were resistant to streptomycin (54.90%), gentamycin (74.50%), co-trimoxazole (70.58%), tetracycline (82.35%), and trimethoprim (62.74%). Current findings revealed significant association between the presence of , , genes in sheep samples. Furthermore, significant association was observed between and genes in goat meat samples. In sheep meat samples, significant differences were identified in resistance to gentamicin, tetracycline, and co-trimoxazole in comparison with other antibiotics. Finally, there were statistically significant differences between the incidences of resistance to gentamicin, tetracycline, and co-trimoxazole in comparison with other antibiotics in all strains. In conclusion, the presence of virulence factors and antibiotic resistance in strains isolated from animal meat samples showed that animals should be considered as a potential reservoir of multidrug-resistant .
该属属于一组革兰氏阴性球杆菌。这些细菌分离自人类和动物来源。抗菌剂在治疗人类和动物的传染病中起着至关重要的作用，在这方面被定义为低毒力的生物体。当前的研究旨在评估从生动物肉样本中分离出的菌株的抗生素抗性特性和毒力因子基因。从伊朗伊斯法罕和沙赫雷克德市随机采集了124只绵羊、162只山羊和95峰骆驼的新鲜肉样。从羊肉样本中分离出的大多数菌株代表（82.35%）、（78.43%）、（78.43%）和I类整合子（96.07%）基因。此外，从绵羊样本中分离出的超过50%的菌株对链霉素（54.90%）、庆大霉素（74.50%）、复方新诺明（70.58%）、四环素（82.35%）和甲氧苄啶（62.74%）耐药。当前的研究结果揭示了绵羊样本中、、基因的存在之间存在显著关联。此外，在山羊肉样本中观察到和基因之间存在显著关联。在羊肉样本中，与其他抗生素相比，在对庆大霉素、四环素和复方新诺明的耐药性方面发现了显著差异。最后，在所有菌株中，与其他抗生素相比，对庆大霉素、四环素和复方新诺明的耐药发生率存在统计学显著差异。总之，从动物肉样本中分离出的菌株中存在毒力因子和抗生素抗性表明，动物应被视为多重耐药的潜在储存宿主。
