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脉搏血氧饱和度测定法:口腔外科门诊全身麻醉期间准确性的评估

Pulse oximetry: evaluation of accuracy during outpatient general anesthesia for oral surgery.

作者信息

Anderson J A, Lambert D M, Kafer E R, Dolan P

出版信息

Anesth Prog. 1988 Mar-Apr;35(2):53-60.

PMID:3166346
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2148593/
Abstract

Pulse oximetry has been shown to be accurate under steady state conditions. In this study, the accuracy of four pulse oximeters are evaluated and compared during outpatient general anesthesia for third molar extractions. The oximeters evaluated are the Nellcor N-100, the Ohmeda 3700, the Novametrix model 500, and the Bird 4400 portable pulse oximeter.Ultralight general anesthesia for oral surgery presents a unique challenge for respiratory monitoring in that patients are often not intubated and commonly experience periods of hyper- and hypoventilation. Airway obstruction, apnea, and laryngospasm may occur easily and patients often vocalize and move during surgery. Because hypoxemia is the primary cause of morbidity and mortality during anesthesia, an accurate, continuous, and noninvasive monitor of oxygenation is critical to risk management.Twenty ASA class I and II patients underwent outpatient general anesthesia for third molar removal using nitrous oxide-oxygen, midazolam, fentanyl, and methohexital. Arterial blood samples were obtained at five-minute intervals during anesthesia, as well as any time a desaturation of >5% occurred, for measurement of arterial SaO(2) with an IL282 CO-Oximeter. These values were compared with simultaneously recorded saturations observed for each pulse oximeter. A total of 122 arterial samples were obtained over a range of PaO(2) from 52-323 mm Hg and observed saturations of 70-100%.The Bird 4400 portable pulse oximeter proved to be the most accurate and reliably predicted arterial saturation under these conditions (y = 1.03x - 2.8, r = 0.85). The Novametrix model 500 pulse oximeter also demonstrated a high degree of accuracy by linear regression analysis, but displayed the lowest correlation coefficient (spread of data points) overall (y = 0.97x + 2.8, r = 0.80.) The Nellcor N-100 pulse oximeter also proved to be highly accurate. (y = 1.05x - 4.1, r = 0.84.) In contrast, regression analysis of the observed saturations obtained with the Ohmeda 3700 pulse oximeter revealed that this unit significantly underestimated arterial saturation (y = 1.20x - 19.6, r = 0.83.)This study demonstrates that despite the rigorous conditions imposed by outpatient general anesthesia for oral surgery, three of the pulse oximeters tested were linearly accurate in predicting arterial oxyhemoglobin saturation over the range of 70-100%. The Ohmeda 3700 was found to significantly underestimate arterial saturation.

摘要

脉搏血氧饱和度测定法已被证明在稳态条件下是准确的。在本研究中,对四种脉搏血氧仪在门诊第三磨牙拔除术全身麻醉期间的准确性进行了评估和比较。所评估的血氧仪分别是Nellcor N - 100、Ohmeda 3700、Novametrix 500型和Bird 4400便携式脉搏血氧仪。口腔外科的超轻型全身麻醉对呼吸监测提出了独特的挑战,因为患者通常不插管,且常经历通气过度和通气不足的时期。气道梗阻、呼吸暂停和喉痉挛可能很容易发生,并且患者在手术期间经常发声和移动。由于低氧血症是麻醉期间发病和死亡的主要原因,准确、连续且无创的氧合监测对于风险管理至关重要。20例美国麻醉医师协会(ASA)I级和II级患者接受了使用氧化亚氮 - 氧气、咪达唑仑、芬太尼和甲己炔巴比妥的门诊第三磨牙拔除术全身麻醉。在麻醉期间每隔5分钟采集动脉血样本,以及在任何血氧饱和度下降>5%时采集样本,用IL282型一氧化碳 - 血氧仪测量动脉血氧饱和度(SaO₂)。将这些值与每个脉搏血氧仪同时记录的饱和度进行比较。在52 - 323 mmHg的动脉血氧分压(PaO₂)范围内共采集了122份动脉样本,观察到的饱和度范围为70 - 100%。在这些条件下,Bird 4400便携式脉搏血氧仪被证明是最准确的,并且能可靠地预测动脉饱和度(y = 1.03x - 2.8,r = 0.85)。通过线性回归分析,Novametrix 500型脉搏血氧仪也显示出高度准确性,但总体上相关系数最低(数据点分布范围)(y = 0.97x + 2.8,r = 0.80)。Nellcor N - 100脉搏血氧仪也被证明高度准确(y = 1.05x - 4.1,r = 0.84)。相比之下,对Ohmeda 3700脉搏血氧仪观察到的饱和度进行回归分析表明,该仪器显著低估了动脉饱和度(y = 1.20x - 19.6,r = 0.83)。本研究表明,尽管口腔外科门诊全身麻醉有严格条件,但所测试的三种脉搏血氧仪在预测70 - 100%范围内的动脉氧合血红蛋白饱和度方面线性准确。发现Ohmeda 3700显著低估动脉饱和度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e61/2148593/a575bc626253/anesthprog00272-0020-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e61/2148593/d9c05ec9da42/anesthprog00272-0019-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e61/2148593/cca2060cfa43/anesthprog00272-0020-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e61/2148593/a575bc626253/anesthprog00272-0020-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e61/2148593/d9c05ec9da42/anesthprog00272-0019-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e61/2148593/cca2060cfa43/anesthprog00272-0020-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e61/2148593/a575bc626253/anesthprog00272-0020-b.jpg

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本文引用的文献

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HYPOXIA IN ANESTHESIA: A REVIEW.麻醉中的低氧血症:综述
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Assessment of two noninvasive monitors of arterial oxygenation in anesthetized man.对麻醉状态下男性的两种动脉氧合无创监测仪的评估。
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Evaluation of pulse oximetry.脉搏血氧饱和度测定法的评估
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Pulse oximetry monitoring of sedated pediatric dental patients.对接受镇静的小儿牙科患者进行脉搏血氧饱和度监测。
Anesth Prog. 1985 Nov-Dec;32(6):237-40.