Goldenberg D L
Department of Medicine, Boston University School of Medicine, MA 02118.
J Rheumatol. 1988 Jun;15(6):992-6.
Research in regard to fibromyalgia has greatly increased during the last 5 years. Initially, investigators concentrated on clinical descriptions and diagnostic criteria. Early pathophysiologic aspects studied included sleep disturbances and psychiatric aspects of the syndrome. More recently, studies have focused on peripheral tissue abnormalities, including sophisticated studies of abnormal muscle metabolism, immunologic and neurotransmitter abnormalities. Future suggested research directions are reviewed.
在过去5年里，关于纤维肌痛的研究大幅增加。最初，研究人员专注于临床描述和诊断标准。早期研究的病理生理方面包括睡眠障碍和该综合征的精神方面。最近，研究集中在外周组织异常上，包括对异常肌肉代谢、免疫和神经递质异常的深入研究。本文对未来建议的研究方向进行了综述。
