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Response to "Three drugs are unnecessary for treating paucibacillary leprosy-A critique of the WHO guidelines".对《治疗少菌型麻风病无需三种药物——对世界卫生组织指南的批评》的回应
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Leprosy.麻风病。
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Effectiveness and safety of multidrug therapy containing clofazimine for paucibacillary leprosy and clarithromycin for rifampicin-resistant leprosy: a systematic review and meta-analysis.含氯法齐明的多药疗法治疗少菌型麻风及含克拉霉素的多药疗法治疗耐利福平麻风的有效性和安全性：一项系统评价和荟萃分析。
Front Med (Lausanne). 2023 May 10;10:1139304. doi: 10.3389/fmed.2023.1139304. eCollection 2023.
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Leprosy treatment: Can we replace opinions with research?麻风病治疗：我们能否用研究取代观点？
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Response to "Three drugs are unnecessary for treating paucibacillary leprosy-A critique of the WHO guidelines".对《治疗少菌型麻风病无需三种药物——对世界卫生组织指南的批评》的回应
PLoS Negl Trop Dis. 2020 Jun 4;14(6):e0008169. doi: 10.1371/journal.pntd.0008169. eCollection 2020 Jun.

本文引用的文献

1
Outcome of 6 months MBMDT in MB patients in Bangladesh- preliminary results.孟加拉国麻风病人6个月多药联合麻风病治疗的结果——初步结果
Lepr Rev. 2016 Jun;87(2):171-82.
2
Single-dose rifampicin chemoprophylaxis protects those who need it least and is not a cost-effective intervention.单剂量利福平化学预防对最不需要它的人起到了保护作用，且并非具有成本效益的干预措施。
PLoS Negl Trop Dis. 2018 Jun 7;12(6):e0006403. doi: 10.1371/journal.pntd.0006403. eCollection 2018 Jun.
3
Uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): Results of an open label, randomized and controlled clinical trial, among multibacillary patients.巴西麻风病患者统一多药疗法（U-MDT/CT-BR）：多菌型患者开放标签、随机对照临床试验结果
PLoS Negl Trop Dis. 2017 Jul 13;11(7):e0005725. doi: 10.1371/journal.pntd.0005725. eCollection 2017 Jul.
4
Leprosy reactions: The predictive value of Mycobacterium leprae-specific serology evaluated in a Brazilian cohort of leprosy patients (U-MDT/CT-BR).麻风反应：在巴西麻风病患者队列（U-MDT/CT-BR）中评估的麻风分枝杆菌特异性血清学的预测价值
PLoS Negl Trop Dis. 2017 Feb 21;11(2):e0005396. doi: 10.1371/journal.pntd.0005396. eCollection 2017 Feb.
5
WHO multidrug therapy for leprosy: epidemiology of default in treatment in Agra district, Uttar Pradesh, India.世界卫生组织的麻风病联合化疗：印度北方邦阿格拉地区治疗中断的流行病学情况
Biomed Res Int. 2015;2015:705804. doi: 10.1155/2015/705804. Epub 2015 Feb 1.
6
Brazilian clinical trial of uniform multidrug therapy for leprosy patients: the correlation between clinical disease types and adverse effects.巴西对麻风病患者进行统一多药物疗法的临床试验：临床疾病类型与不良反应之间的相关性。
Mem Inst Oswaldo Cruz. 2012 Dec;107 Suppl 1:74-8. doi: 10.1590/s0074-02762012000900013.
7
Hypersensitivity reactions to dapsone: a systematic review.达普司酮过敏反应：系统评价。
Acta Derm Venereol. 2012 Mar;92(2):194-9. doi: 10.2340/00015555-1268.
8
Comparative study of uniform-MDT and WHO MDT in Pauci and Multi bacillary leprosy patients over 24 months of observation.对少菌型和多菌型麻风患者进行24个月观察，比较统一多学科团队治疗（uniform-MDT）与世界卫生组织多学科团队治疗（WHO MDT）的研究。
Lepr Rev. 2009 Jun;80(2):143-55.
9
MDT-MB therapy in paucibacillary leprosy: a clinicopathological assessment.少菌型麻风的多药联合化疗：临床病理评估
Indian J Dermatol Venereol Leprol. 2005 Jul-Aug;71(4):242-5. doi: 10.4103/0378-6323.16614.
10
The INFIR Cohort Study: investigating prediction, detection and pathogenesis of neuropathy and reactions in leprosy. Methods and baseline results of a cohort of multibacillary leprosy patients in north India.INFIR队列研究：调查麻风病中神经病变及反应的预测、检测和发病机制。印度北部多菌型麻风病患者队列的方法和基线结果。
Lepr Rev. 2005 Mar;76(1):14-34.

Three drugs are unnecessary for treating paucibacillary leprosy-A critique of the WHO guidelines.

作者信息

Lockwood Diana N J, Lambert Saba, Srikantam Aparna, Darlong Joydeepa, Pai V V, Butlin C Ruth, de Barros Barbara, Negera Edessa, Walker Stephen L

机构信息

London School of Hygiene & Tropical Medicine, Faculty of Infectious Diseases, London, United Kingdom.

LEPRA-Blue Peter Public Health and Research Center, Hyderabad, India.

出版信息

PLoS Negl Trop Dis. 2019 Oct 31;13(10):e0007671. doi: 10.1371/journal.pntd.0007671. eCollection 2019 Oct.

DOI:10.1371/journal.pntd.0007671
PMID:31671087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6822700/
Abstract
摘要