精神分裂症的边缘系统病理学：内嗅区——一项形态计量学研究。
Limbic pathology in schizophrenia: the entorhinal region--a morphometric study.
作者信息
Falkai P, Bogerts B, Rozumek M
机构信息
C. u. O. Vogt-Institute of Brain Research, University of Düsseldorf, F.R.G.
出版信息
Biol Psychiatry. 1988 Sep;24(5):515-21. doi: 10.1016/0006-3223(88)90162-x.
PMID:3167140
Abstract
The volume of the entorhinal region is significantly reduced in postmortem brains of schizophrenics compared with controls (p less than 0.017). In addition, a significant reduction of neurons (p less than 0.017), but no significant increase in absolute glial cell numbers, is found. These results are consistent with the hypothesis that structural changes in the medial temporal lobe of schizophrenics may be developmental in origin.
摘要
与对照组相比，精神分裂症患者死后大脑内嗅区的体积显著减小（p<0.017）。此外，还发现神经元数量显著减少（p<0.017），但神经胶质细胞的绝对数量没有显著增加。这些结果与精神分裂症患者内侧颞叶的结构变化可能起源于发育过程的假说一致。
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