Kolobkov S L, Komissarova E V
Biull Eksp Biol Med. 1988 Sep;106(9):341-4.
NIH 3T3 cells were transfected by plasmid containing v-src under control of hormone-regulated LTR MMTV (pMLsrc10). This plasmid caused the foci of morphologically transformed cells. The transformed cells induced rapidly growing tumours in nude mice. In the presence of dexamethasone the efficiency of NIH 3T3 cell transformation increased ten times, while tumourigenicity remained unchanged.
用含有受激素调节的长末端重复序列（LTR）MMTV控制的v-src的质粒（pMLsrc10）转染NIH 3T3细胞。该质粒导致形态转化细胞形成集落。转化细胞在裸鼠中诱导出快速生长的肿瘤。在地塞米松存在的情况下，NIH 3T3细胞转化效率提高了10倍，而成瘤性保持不变。
