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[实验中骨骼肌线粒体对深度低温的结构反应]

[Structural reaction of skeletal muscle mitochondria to deep hypothermia in the experiment].

作者信息

Veriaskin V V, Filiushina E E, Shmerling M D

出版信息

Biull Eksp Biol Med. 1988 Sep;106(9):361-3.

PMID:3167193
Abstract

The reaction of locomotor muscle mitochondria was studied in white rats during different periods of deep hypothermia. An acute exposure to cold produced substantial changes of the muscle cellular mitochondrial apparatus, such as matrix swelling, crysts destruction with a significant decrease in mitochondrial profiles on the periphery of muscle fibers. Destructive and degenerative mitochondrial lesions were greater in prolonged hypothermia and subsequent warming. Such structural reaction of locomotor muscle mitochondria could reveal a substantial insufficiency of the muscle cellular energy apparatus during experimental hypothermia.

摘要

在深低温的不同阶段对白鼠运动肌线粒体的反应进行了研究。急性冷暴露使肌细胞线粒体装置发生了显著变化,如基质肿胀、嵴破坏,肌纤维周边线粒体轮廓显著减少。在长时间低温及随后复温过程中,线粒体的破坏和退行性病变更为严重。运动肌线粒体的这种结构反应可能揭示了实验性低温期间肌细胞能量装置的严重不足。

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