Wong Kristine S, Barletta Justine A
Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
Surg Pathol Clin. 2019 Dec;12(4):901-919. doi: 10.1016/j.path.2019.08.008.
This article examines more uncommon thyroid entities, including anaplastic thyroid carcinoma, poorly differentiated thyroid carcinoma, rare papillary thyroid carcinoma variants, medullary thyroid carcinoma, non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP), and multiple adenomatous nodules in the setting of Cowden syndrome. These entities were chosen based on their clinical significance and because they can be diagnostically challenging due to their morphologic diversity and overlap with other thyroid tumors. This article addresses the diagnostic features of each entity, focusing on how to avoid potential pitfalls and mimics while also highlighting the clinical implications of each diagnosis.
本文探讨了更罕见的甲状腺疾病，包括未分化甲状腺癌、低分化甲状腺癌、罕见的乳头状甲状腺癌变体、髓样甲状腺癌、具有乳头状核特征的非侵袭性滤泡性甲状腺肿瘤（NIFTP）以及考登综合征背景下的多个腺瘤性结节。选择这些疾病是基于它们的临床意义，以及由于其形态学多样性和与其他甲状腺肿瘤的重叠性，在诊断上可能具有挑战性。本文阐述了每种疾病的诊断特征，重点在于如何避免潜在的陷阱和误诊，同时也强调了每种诊断的临床意义。
