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胡志明市的颗粒物空气污染与幼儿急性下呼吸道感染(ALRI)住院风险

Particulate air pollution in Ho Chi Minh city and risk of hospital admission for acute lower respiratory infection (ALRI) among young children.

机构信息

Faculty of Environmental Sciences, VNU University of Science, Vietnam National University, Hanoi, Viet Nam.

The Institute of Research and Development, Duy Tan University, Da Nang City, Viet Nam; Department of Environmental Health, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh, Viet Nam.

出版信息

Environ Pollut. 2020 Feb;257:113424. doi: 10.1016/j.envpol.2019.113424. Epub 2019 Oct 18.

DOI:10.1016/j.envpol.2019.113424
PMID:31672367
Abstract

High levels of air pollutants in Vietnam, especially particulate matters including PM, can be important risk factors for respiratory diseases among children of the country. However, few studies on the effects of ambient air pollution on human health have been conducted in Vietnam so far. The aim of this study is to examine the association between PM and hospital admission due to acute lower respiratory infection (ALRI) among children aged < 5 years old in Ho Chi Minh city, the largest city of Vietnam. Data relating PM and hospital admission were collected from February 2016-December 2017 and a time series regression analysis was performed to examine the relationship between PM and hospital admission including the delayed effect up to three days prior to the admission. We found that each 10 μg/m increase in PM was associated with an increase of 3.51 (95%CI: 0.96-6.12) risk of ALRI admission among children. According to the analysis, male children are more sensitive to exposure to PM than females, while children exposed to PM are more likely to be infected with acute bronchiolitis than with pneumonia. The study demonstrated that young children in HCMC are at increased risk of ALRI admissions due to the high level of PM concentration in the city's ambient air.

摘要

越南的空气污染物水平较高,尤其是颗粒物(包括 PM),这些物质可能是该国儿童患呼吸道疾病的重要危险因素。然而,迄今为止,越南对环境空气污染对人类健康影响的研究甚少。本研究旨在检验胡志明市(越南最大的城市) 5 岁以下儿童因急性下呼吸道感染(ALRI)住院与 PM 之间的关联。从 2016 年 2 月至 2017 年 12 月收集了与 PM 和住院相关的数据,并进行了时间序列回归分析,以检验 PM 与住院之间的关系,包括入院前三天的滞后效应。结果表明,PM 每增加 10μg/m,儿童患 ALRI 的风险就会增加 3.51(95%CI:0.96-6.12)。根据分析,男童比女童对 PM 暴露更敏感,而暴露于 PM 的儿童更易患急性细支气管炎,而不是肺炎。研究表明,由于胡志明市环境空气中的 PM 浓度较高,该市的幼儿患 ALRI 的风险增加。

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