Chen Lu, Yang Zhongcheng, Chen Yingdong, Wang Wenhan, Shao Chen, Chen Lanfang, Ming Xiaoyan, Zhang Qiuju
Department of Biostatistics, School of Public Health, Harbin Medical University.
Yichang Center for Disease Control and Prevention.
Environ Health Prev Med. 2025;30:16. doi: 10.1265/ehpm.24-00373.
There is growing evidence that the occurrence and severity of respiratory diseases in children are related to the concentration of air pollutants. Nonetheless, evidence regarding the association between short-term exposure to air pollution and outpatient visits for respiratory diseases in children remains limited. Outpatients cover a wide range of disease severity, including both severe and mild cases, some of which may need to be transferred to inpatient treatment. This study aimed to quantitatively evaluate the impact of short-term ambient air pollution exposure on outpatient visits for respiratory conditions in children.
This study employed data of the Second People's Hospital of Yichang from January 1, 2016 to December 31, 2023, to conduct a time series analysis. The DLNM approach was integrated with a generalized additive model to examine the daily outpatient visits of pediatric patients with respiratory illnesses in hospital, alongside air pollution data obtained from monitoring stations. Adjustments were made for long-term trends, meteorological variables, and other influencing factors.
A nonlinear association was identified between PM, PM, O, NO, SO, CO levels and the daily outpatient visits for respiratory diseases among children. All six pollutants exhibit a hysteresis impact, with varying durations ranging from 4 to 6 days. The risks associated with air pollutants differ across various categories of children's respiratory diseases; notably, O and CO do not show statistical significance concerning the risk of chronic respiratory conditions. Furthermore, the results of infectious respiratory diseases were similar with those of respiratory diseases.
Our results indicated that short-term exposure to air pollutants may contribute to an increased incidence of outpatient visits for respiratory illnesses among children, and controlling air pollution is important to protect children's health.
越来越多的证据表明,儿童呼吸道疾病的发生和严重程度与空气污染物浓度有关。尽管如此,关于儿童短期接触空气污染与呼吸道疾病门诊就诊之间关联的证据仍然有限。门诊患者涵盖了广泛的疾病严重程度,包括重症和轻症病例,其中一些可能需要转为住院治疗。本研究旨在定量评估短期暴露于环境空气污染对儿童呼吸道疾病门诊就诊的影响。
本研究采用宜昌市第二人民医院2016年1月1日至2023年12月31日的数据进行时间序列分析。将分布滞后非线性模型(DLNM)方法与广义相加模型相结合,以研究医院中患有呼吸道疾病的儿科患者的每日门诊就诊情况,同时结合从监测站获得的空气污染数据。对长期趋势、气象变量和其他影响因素进行了调整。
确定了颗粒物(PM)、臭氧(O₃)、二氧化氮(NO₂)、二氧化硫(SO₂)、一氧化碳(CO)水平与儿童呼吸道疾病每日门诊就诊之间存在非线性关联。所有六种污染物均表现出滞后效应,持续时间从4天到6天不等。空气污染物相关风险在儿童各类呼吸道疾病中有所不同;值得注意的是,O₃和CO在慢性呼吸道疾病风险方面未显示出统计学意义。此外,感染性呼吸道疾病的结果与呼吸道疾病的结果相似。
我们的结果表明,短期接触空气污染物可能导致儿童呼吸道疾病门诊就诊率增加,控制空气污染对保护儿童健康很重要。