Centro de Investigación en Salud Materna e Infantil, Centro de Investigación para el Desarrollo Integral y Sostenible, Universidad Peruana Cayetano Heredia, Lima, Peru.
School of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru.
J Glob Health. 2019 Dec;9(2):020805. doi: 10.7189/jogh.09.020805.
Childhood diarrhoea mortality has declined substantially in Peru in recent decades. We documented trends in childhood diarrhoea mortality from 1980 to 2015, along with trends in coverage of diarrhoea-related interventions and risk factors, to identify the main drivers of mortality reduction.
We conducted desk reviews on social determinants, policies and programmes, and diarrhoea-related interventions implemented during the study period. We reviewed different datasets on child mortality, and on coverage of diarrhoea-related interventions. We received input from individuals familiar with implementation of diarrhoea-related policies and programmes. We used the Lives Saved Tool () to help explain the reasons for the decline in diarrhoea mortality from 1980 to 2015 and to predict additional reduction with further scale up of diarrhoea-related interventions by 2030.
In Peru under-five diarrhoea mortality declined from 23.3 in 1980 to 0.8 per 1000 livebirths in 2015. The percentage of under-five diarrhoea deaths as related to total under-five deaths was reduced from 17.8% in 1980 to 4.9% in 2015. Gross domestic product increased and poverty declined from 1990 to 2015. Access to improved water increased from 56% in 1986 to 79.3% in 2015. Oral rehydrating salts (ORS) use during an episode of diarrhoea increased from 3.6% in 1986 to 32% in 2015. Vertical programmes focused on diarrhoea management with ORS were implemented successfully in the 1980s and 1990s, and were replaced by integrated crosscutting interventions since the early 2000s. LiST analyses showed that about half (53.9%) of the reduction in diarrhoea mortality could be attributed to improved water, sanitation and hygiene, 25.0% to direct diarrhoea interventions and 21.1% to nutrition. The remaining mortality could be reduced by three-quarters by 2030 with improved diarrhoea treatment and further with enhanced breastfeeding practices and reduction in stunting. does not take into account the role of social determinants.
The reduction of diarrhoeal under-five mortality in Peru can be explained by a combination of factors, including improvement of social determinants, child nutrition, diarrhoea treatment with ORS and prevention with rotavirus vaccine and increased access to water and sanitation. The already low rate of diarrhoea mortality could be further reduced by a number of interventions, especially additional use of ORS and zinc for diarrhoea treatment. Peru is a remarkable example of a country that was able to reduce childhood diarrhoea mortality by implementing interventions through vertical programmes initially, and afterwards through implementation of integrated multisectoral packages targeting prevalent illnesses and multi-causal problems like stunting.
近几十年来,秘鲁儿童腹泻死亡率大幅下降。我们记录了 1980 年至 2015 年期间儿童腹泻死亡率的趋势,以及与腹泻相关的干预措施和风险因素的覆盖范围的趋势,以确定死亡率降低的主要驱动因素。
我们对研究期间实施的社会决定因素、政策和方案以及与腹泻相关的干预措施进行了案头审查。我们审查了不同的儿童死亡率数据集和与腹泻相关的干预措施的覆盖范围。我们收到了熟悉腹泻相关政策和方案实施情况的个人的意见。我们使用挽救生命工具(Lives Saved Tool)来帮助解释 1980 年至 2015 年腹泻死亡率下降的原因,并预测通过 2030 年进一步扩大与腹泻相关的干预措施,将进一步减少腹泻死亡率。
秘鲁 5 岁以下儿童腹泻死亡率从 1980 年的每 1000 例活产 23.3 例下降到 2015 年的 0.8 例。1980 年,腹泻导致的 5 岁以下儿童死亡占 5 岁以下儿童总死亡的 17.8%,2015 年降至 4.9%。1990 年至 2015 年,国内生产总值增加,贫困减少。1986 年,获得改良水的比例从 56%增加到 2015 年的 79.3%。1986 年,腹泻发作时使用口服补液盐(ORS)的比例从 3.6%增加到 2015 年的 32%。20 世纪 80 年代和 90 年代,成功实施了以腹泻管理为重点的垂直规划,自 21 世纪初以来,这些规划被纳入综合性跨部门干预措施。List 分析表明,腹泻死亡率降低的一半(53.9%)可归因于水、环境卫生和个人卫生的改善,25.0%可归因于直接的腹泻干预措施,21.1%可归因于营养。通过改善腹泻治疗,进一步加强母乳喂养实践和减少发育迟缓,到 2030 年,还可以将剩余的死亡率降低四分之三。List 没有考虑社会决定因素的作用。
秘鲁五岁以下儿童腹泻死亡率的降低可以归因于多种因素的综合作用,包括社会决定因素、儿童营养、ORS 治疗腹泻和轮状病毒疫苗预防以及获得水和卫生设施的改善。通过进一步增加口服补液盐(ORS)和锌的使用来治疗腹泻,进一步降低腹泻死亡率的许多干预措施已经非常有效。秘鲁是一个显著的例子,它通过最初实施垂直规划,随后实施针对流行疾病和发育迟缓等多因性问题的综合性多部门方案,成功降低了儿童腹泻死亡率。