Ifakara Health Institute, Dar-es-Salaam, Tanzania.
World Health Organization, Dar-es-Salaam, Tanzania.
J Glob Health. 2019 Dec;9(2):020806. doi: 10.7189/jogh.09.020806.
Tanzania has made great progress in reducing diarrhea mortality in under- five children. We examined factors associated with the decline and projected the impact of scaling up interventions or reducing risk factors on diarrhea deaths.
We reviewed economic, health, and diarrhea-related policies, reports and programs implemented during 1980 to 2015. We used the Lives Saved Tool to determine the percentage reduction in diarrhea-specific mortality attributable to changes in coverage of the interventions and risk factors, including direct diarrhea-related interventions, nutrition, and water, sanitation and hygiene (WASH). We projected the number of diarrhea deaths that could be prevented in 2030, assuming near universal coverage of different intervention packages.
Diarrhea-specific mortality among under-five children in Tanzania declined by 89% from 35.3 deaths per 1000 live births in 1980 to 3.9 deaths per 1000 live births in 2015. Factors associated with diarrhea-specific under-five mortality reduction included oral rehydration solution (ORS) use, changes in stunting prevalence, vitamin A supplementation, rotavirus vaccine, change in wasting prevalence and change in age-appropriate breastfeeding practices. Universal coverage of direct diarrhea, nutrition and WASH interventions has the potential reduce the diarrhea-specific mortality rate by 90%.
Scaling up of a few key childhood interventions such as ORS and nutrition, and reducing the prevalence of stunting would address the remaining diarrhea-specific under-five mortality by 2030.
坦桑尼亚在降低五岁以下儿童腹泻死亡率方面取得了巨大进展。我们研究了与死亡率下降相关的因素,并预测了扩大干预措施或降低风险因素对腹泻死亡的影响。
我们回顾了 1980 年至 2015 年期间实施的经济、卫生和腹泻相关政策、报告和方案。我们使用生命挽救工具来确定因干预措施和风险因素覆盖率变化而导致的腹泻特异性死亡率降低的百分比,包括直接与腹泻相关的干预措施、营养、水、环境卫生和个人卫生。我们假设不同干预方案的覆盖率接近普遍,预测了 2030 年可能预防的腹泻死亡人数。
坦桑尼亚五岁以下儿童腹泻特异性死亡率从 1980 年每 1000 例活产 35.3 例下降到 2015 年的 3.9 例,下降了 89%。与腹泻特异性五岁以下儿童死亡率降低相关的因素包括口服补液盐(ORS)的使用、发育迟缓流行率的变化、维生素 A 补充、轮状病毒疫苗、消瘦流行率的变化和适当年龄的母乳喂养行为的变化。全面覆盖直接治疗腹泻、营养和水环境卫生干预措施,有可能将腹泻特异性死亡率降低 90%。
扩大 ORS 和营养等少数关键儿童干预措施的规模,并降低发育迟缓的流行率,将有助于在 2030 年前解决剩余的腹泻特异性五岁以下儿童死亡率问题。