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基于壳聚糖的磁性纳米复合材料的结构与抗肿瘤特性数据集

Structural and antitumoral characteristic dataset of the chitosan based magnetic nanocomposite.

作者信息

Tashakkorian Hamed, Hasantabar Vahid, Golpour Monire

机构信息

Cellular and Molecular Biology Research Center (CMBRC), Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Department of Pharmacology, School of Medicine, Babol University of Medical Sciences, Babol, Iran.

出版信息

Data Brief. 2019 Sep 28;27:104583. doi: 10.1016/j.dib.2019.104583. eCollection 2019 Dec.

DOI:10.1016/j.dib.2019.104583
PMID:31673586
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6817675/
Abstract

The evaluation on the characteristic dataset and figures presented here, are related to our latest research data entitled "Fabrication of chitosan based magnetic nanocomposite by click reaction strategy; evaluation of nanometric and Cytotoxic characteristics" [1]. FTIR, Vibrating Sample Magnetometer (VSM) measurements, Xray diffraction (XRD) information and the resulted figures for structural confirmation of the prepared chitosan based nanocomposite are presented in this article. The morphological changes of the Fibroblast, Saos, MCF7 and Hela cell lines after treatment with the mention compound were displayed. The additional adsorption data for the synthesized nanobiocomposite were also demonstrated with graphs.

摘要

此处对特征数据集和图表的评估,与我们最新的研究数据相关,该研究数据题为“通过点击反应策略制备基于壳聚糖的磁性纳米复合材料;纳米尺寸和细胞毒性特征评估”[1]。本文展示了傅里叶变换红外光谱(FTIR)、振动样品磁强计(VSM)测量结果、X射线衍射(XRD)信息以及用于所制备的基于壳聚糖的纳米复合材料结构确认的所得图表。展示了用上述化合物处理后成纤维细胞、骨肉瘤细胞、人乳腺癌细胞MCF7和人宫颈癌细胞Hela的形态变化。还通过图表展示了合成的纳米生物复合材料的额外吸附数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/6817675/693caacee386/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/6817675/caf35c2ec722/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/6817675/487c66b1bec9/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/6817675/270b173ad5eb/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/6817675/2c57f8b22fd9/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/6817675/693caacee386/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/6817675/caf35c2ec722/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/6817675/487c66b1bec9/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/6817675/270b173ad5eb/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/6817675/2c57f8b22fd9/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/704f/6817675/693caacee386/gr5.jpg

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本文引用的文献

1
Fabrication of chitosan based magnetic nanocomposite by click reaction strategy; evaluation of nanometric and cytotoxic characteristics.通过点击反应策略制备壳聚糖基磁性纳米复合材料;纳米特性和细胞毒性评估。
Carbohydr Polym. 2019 Nov 15;224:115163. doi: 10.1016/j.carbpol.2019.115163. Epub 2019 Aug 8.
2
Click chemistry-based synthesis and anticancer activity evaluation of novel C-14 1,2,3-triazole dehydroabietic acid hybrids.点击化学法合成新型 C-14 1,2,3-三唑枞酸 hybrids 及其抗癌活性评价。
Eur J Med Chem. 2017 Sep 29;138:1042-1052. doi: 10.1016/j.ejmech.2017.07.049. Epub 2017 Jul 24.
3
The application of click chemistry in the synthesis of agents with anticancer activity.
点击化学在具有抗癌活性的药物合成中的应用。
Drug Des Devel Ther. 2015 Mar 12;9:1585-99. doi: 10.2147/DDDT.S56038. eCollection 2015.