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初始放射治疗计划的意外计算机断层扫描重新模拟:相关因素及临床影响

Unforeseen Computed Tomography Resimulation for Initial Radiation Planning: Associated Factors and Clinical Impact.

作者信息

Metzger April, Renz Paul, Hasan Shaakir, Karlovits Stephen, Sohn Jason, Gresswell Steven

机构信息

Division of Radiation Oncology, Allegheny Health Network, Pittsburgh, Pennsylvania.

Division of Radiation Oncology, West Virginia University, Morgantown, West Virginia.

出版信息

Adv Radiat Oncol. 2019 Jun 20;4(4):716-721. doi: 10.1016/j.adro.2019.06.002. eCollection 2019 Oct-Dec.

Abstract

PURPOSE

Repeat computed tomography (CT) simulation is problematic because of additional expense of clinic resources, patient inconvenience, additional radiation exposure, and treatment delay. We investigated the factors and clinical impact of unplanned CT resimulations in our network.

METHODS AND MATERIALS

We used the billing records of 18,170 patients treated at 5 clinics. A total of 213 patients were resimulated before their first treatment. The disease site, location, use of 4-dimensional CT (4DCT), contrast, image fusion, and cause for resimulation were recorded. Odds ratios determined statistical significance.

RESULTS

Our total rate of resimulation was 1.2%. Anal/colorectal ( < .001) and head and neck ( < .001) disease sites had higher rates of resimulation. Brain ( = .001) and lung/thorax ( = .008) had lower rates of resimulation. The most common causes for resimulation were setup change (11.7%), change in patient anatomy (9.8%), and rectal filling (8.5%). The resimulation rate for 4DCTs was 3.03% compared with 1.0% for non-4DCTs ( < .001). Median time between simulations was 7 days.

CONCLUSIONS

The most common sites for resimulation were anal/colorectal and head and neck, largely because of change in setup or changes in anatomy. The 4DCT technique correlated with higher resimulation rates. The resimulation rate was 1.2%, and median treatment delay was 7 days. Further studies are warranted to limit the rate of resimulation.

摘要

目的

重复计算机断层扫描(CT)模拟存在问题,因为会增加临床资源成本、给患者带来不便、增加辐射暴露并导致治疗延迟。我们调查了本网络中计划外CT重新模拟的因素及其临床影响。

方法和材料

我们使用了5家诊所18170例患者的计费记录。共有213例患者在首次治疗前进行了重新模拟。记录疾病部位、位置、四维CT(4DCT)的使用、对比剂、图像融合以及重新模拟的原因。优势比确定统计学意义。

结果

我们的重新模拟总率为1.2%。肛门/结直肠(<.001)和头颈部(<.001)疾病部位的重新模拟率较高。脑部(=.001)和肺/胸部(=.008)的重新模拟率较低。重新模拟最常见的原因是设置改变(11.7%)、患者解剖结构改变(9.8%)和直肠充盈(8.5%)。4DCT的重新模拟率为3.03%,而非4DCT为1.0%(<.001)。两次模拟之间的中位时间为7天。

结论

重新模拟最常见的部位是肛门/结直肠和头颈部,主要原因是设置改变或解剖结构变化。4DCT技术与较高的重新模拟率相关。重新模拟率为1.2%,中位治疗延迟为7天。有必要进行进一步研究以限制重新模拟率。

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