Alward Kayla J, Bohlen Jillian F
Department of Animal and Dairy Science, University of Georgia, Athens, GA, USA.
Reprod Domest Anim. 2020 Jan;55(1):3-10. doi: 10.1111/rda.13583. Epub 2019 Nov 27.
Anti-Müllerian hormone (AMH) is produced by granulosa cells of early-antral follicles found on the ovary. After production, it enters circulation and can be detected from a blood sample with an ELISA. Multiple works have found that circulating AMH is a reliable marker of the antral follicle population (AFP) of an animal as well as directly correlated to an animal's response to a superovulation protocol. Research has also found high repeatability within an animal's oestrous cycle. Further use of AMH may be valuable as a reproductive management tool, based on previous research linking productive life with circulating AMH in heifers and success to various breeding protocols by AMH concentration. The aim of this review was to summarize previous works describing basic function of AMH as well as explore recent research examining AMH as a reproductive tool and measurement of fertility in dairy animals.
抗苗勒管激素（AMH）由卵巢上早期窦状卵泡的颗粒细胞产生。产生后，它进入血液循环，可通过酶联免疫吸附测定（ELISA）从血样中检测到。多项研究发现，循环中的AMH是动物窦状卵泡数量（AFP）的可靠标志物，并且与动物对超数排卵方案的反应直接相关。研究还发现，在动物的发情周期内，AMH具有高度重复性。基于之前将产犊寿命与小母牛循环中的AMH以及通过AMH浓度对各种繁殖方案的成功联系起来的研究，进一步使用AMH作为繁殖管理工具可能具有重要价值。本综述的目的是总结之前描述AMH基本功能的研究，以及探讨最近将AMH作为繁殖工具和奶牛生育能力指标的研究。
