Pérez-Soto Rafael Humberto, Ponce de León-Ballesteros Guillermo, Montalvo-Hernández Jorge, Sierra-Salazar Mauricio, Pantoja Millán Juan Pablo, Herrera-Hernández Miguel Francisco, Velázquez-Fernández David
Endocrine and Advanced Laparoscopic Surgery Service, Department of Surgery, National Institute for Health Sciences and Nutrition Salvador Zubirán, Mexico City, Mexico.
Endocrine Surgery, North Central Hospital PEMEX, Mexico City, Mexico.
J Laparoendosc Adv Surg Tech A. 2019 Dec;29(12):1526-1531. doi: 10.1089/lap.2019.0537. Epub 2019 Nov 1.
Transoral endoscopic thyroidectomy by vestibular approach (TOETVA) is a relatively new technique for the surgical treatment of thyroid diseases. We present the initial experience of a reference hospital of Mexico with TOETVA. This is a comparative retrospective study of cases (TOETVA) and controls (open thyroidectomy) treated by the endocrine surgeons between July 2017 and April 2019. Cases were patients of any gender, older than 18 years of age, with malignant thyroid nodules <2 cm or undetermined <5 cm without extrathyroidal extension and no lymph node or distant metastasis. Demographic, operative, and postoperative data were obtained and analyzed. Twenty patients were surgically treated by TOETVA during the study period. Controls were paired based on type of surgery and dominant thyroid nodule. Ninety percent of the patients had a definitive diagnosis of malignancy. No statistically significant differences were found in age, BMI, length of stay, thyroid lobes size, and complication rates. Operative time was longer in TOETVA (216.7 ± 62.5 vs. 153.9 ± 49.25 minutes; test < .0001) and intraoperative blood loss was lesser for the TOETVA group (38.25 ± 38.9 vs. 101.8 ± 126.6 mL; test < .04). TOETVA is a feasible and relatively safe surgical technique for patients with benign and malignant thyroid diseases. Complication rates seem to be comparable with conventional open technique with lesser intraoperative bleeding; nevertheless, it requires longer operative times.
经口前庭入路内镜甲状腺切除术(TOETVA)是一种用于治疗甲状腺疾病的相对较新的手术技术。我们介绍了墨西哥一家参考医院开展TOETVA的初步经验。这是一项对2017年7月至2019年4月期间内分泌外科医生治疗的病例(TOETVA)和对照(开放性甲状腺切除术)进行的比较性回顾性研究。病例为年龄大于18岁的任何性别的患者,甲状腺恶性结节<2 cm或不确定结节<5 cm,无甲状腺外侵犯,无淋巴结或远处转移。获取并分析了人口统计学、手术和术后数据。在研究期间,20例患者接受了TOETVA手术治疗。根据手术类型和主要甲状腺结节对对照组进行配对。90%的患者被明确诊断为恶性肿瘤。在年龄、体重指数、住院时间、甲状腺叶大小和并发症发生率方面未发现统计学上的显著差异。TOETVA的手术时间较长(216.7±62.5 vs. 153.9±49.25分钟;检验P<0.0001),而TOETVA组的术中出血量较少(38.25±38.9 vs. 101.8±126.6 mL;检验P<0.04)。对于良性和恶性甲状腺疾病患者,TOETVA是一种可行且相对安全的手术技术。并发症发生率似乎与传统开放技术相当,术中出血较少;然而,它需要更长的手术时间。