Şafak Özgen, Gürsoy Ozan Mustafa, Karakoyun Süleyman, Çağdaş Metin, Dinç Asarcıklı Lale, Avcı Demir Fulya, Ersoy İbrahim, Akyüz Abdurrahman, Arıcan Özlük Özlem, Er Fahri, Baktır Ahmet Oğuz, Yesin Mahmut, Eren Hayati, Sungur Aylin, Kurmuş Özge, Emren Volkan, Yakar Tülüce Selcen, Akyıldız Akçay Filiz, Akıl Mehmet Ata, Makca Tuba, Ergene Oktay, Özkan Mehmet
Department Of Cardiology, Burdur State Hospital, Burdur, Turkey.
Department Of Cardiology, İzmir Atatürk Training And Research Hospital,i̇zmir, Turkey.
Anatol J Cardiol. 2019 Nov;22(5):262-270. doi: 10.14744/AnatolJCardiol.2019.45845.
Normal reference values for the cardiac chambers are widely based on cohorts from European or American populations. In this study, we aimed to obtain normal echocardiographic measurements of healthy Turkish volunteers to reveal the age, gender, and geographical region dependent differences between Turkish populations and other populations.
Among 31 collaborating institutions from all regions of Turkey, 1154 healthy volunteers were enrolled in this study. Predefined protocols were used for all participants during echocardiographic examination. Blood biochemical parameters were also obtained for all patients on admission. The American Society of Echocardiography and European Association of Cardiovascular Imaging recommendations were used to assess the echocardiographic cardiac chamber quantification.
The study included 1154 volunteers (men: 609; women: 545), with a mean age of 33.5±11 years. Compared to men, women had a smaller body surface area, lower blood pressure and heart rate, lower hemoglobin, total cholesterol, lower low-density lipoprotein (LDL) levels, and higher high density lipoprotein (HDL) levels. Cardiac chambers were also smaller in women and their size varied with age. When we compared the regions in Turkey, the lowest values of left cardiac chamber indices were seen in the Marmara region and the highest values were observed in the Mediterranean region. Regarding the right cardiac indices, the Mediterranean region reported the lowest values, while the Black Sea region and the Eastern Anatolia region reported the highest values.
This is the first study that evaluates the normal echocardiographic reference values for a healthy Turkish population. These results may provide important reference values that could be useful in routine clinical practice as well as in further clinical trials. (.
心脏腔室的正常参考值广泛基于欧洲或美国人群的队列研究。在本研究中，我们旨在获取健康土耳其志愿者的正常超声心动图测量值，以揭示土耳其人群与其他人群之间年龄、性别和地理区域相关的差异。
在来自土耳其所有地区的31个合作机构中，1154名健康志愿者参与了本研究。超声心动图检查期间，所有参与者均采用预定义方案。所有患者入院时还获取了血液生化参数。美国超声心动图学会和欧洲心血管影像协会的建议用于评估超声心动图心脏腔室的量化。
该研究纳入了1154名志愿者（男性：609名；女性：545名），平均年龄为33.5±11岁。与男性相比，女性的体表面积较小，血压和心率较低，血红蛋白、总胆固醇、低密度脂蛋白（LDL）水平较低，高密度脂蛋白（HDL）水平较高。女性的心脏腔室也较小，且其大小随年龄变化。当我们比较土耳其的不同地区时，马尔马拉地区左心腔指数最低，地中海地区最高。关于右心指数，地中海地区报告的值最低，而黑海地区和东安纳托利亚地区报告的值最高。
这是第一项评估健康土耳其人群正常超声心动图参考值的研究。这些结果可能提供重要的参考值，对常规临床实践以及进一步的临床试验都可能有用。
