Gerosa M, Raumer R, Amadori G, Semenzato G, Gasparotto G, Carteri A
J Neurosurg Sci. 1979 Jul-Sep;23(3):165-75.
A preliminary report on the immunological monitoring of primary intracranial neoplasms is presented. The most important findings concerning B-cells and T-cells mediated immunity and delayed hypersensitivity reactions in this kind of patients, are discussed. Among the fairly significant immunobiological pictures, the Authors stress the "normal behaviour" of the B-cells dependent pool, the undebatable depression of the delayed hypersensitivity reactions, and the noticeable failure of the T-cell dependent pool, particularly marked in malignant gliomas, which are also characterized by the presence of cells with natural cytotoxic activity.
本文给出了一份关于原发性颅内肿瘤免疫监测的初步报告。讨论了这类患者中与B细胞和T细胞介导的免疫以及迟发型超敏反应相关的最重要发现。在这些相当显著的免疫生物学表现中，作者强调了B细胞依赖池的“正常行为”、迟发型超敏反应无可争议的降低以及T细胞依赖池明显的功能障碍，这在恶性胶质瘤中尤为明显，恶性胶质瘤还具有具有天然细胞毒性活性的细胞。
