Laboratoire de Photonique Quantique et Moléculaire (LPQM), UMR 8537, Ecole Normale Supérieure Paris Saclay, CentraleSupélec, CNRS, Université Paris-Saclay, 61 avenue du Président Wilson, 94235 Cachan, France.
Photophysique et Photochimie Supramoléculaires et Macromoléculaires (PPSM), UMR 8531, Ecole Normale Supérieure Paris Saclay, CNRS, Université Paris-Saclay, 61 avenue du Président Wilson, 94235 Cachan, France.
Biosensors (Basel). 2019 Nov 1;9(4):129. doi: 10.3390/bios9040129.
In this work, we report on the development of a newly synthesized photoactive reversible azobenzene derived surfactant polymer, which enables active and fast control of the merging of microdroplets in microfluidic chambers, driven by a pulsed UV laser optical stimulus and the well known - photo-isomerisation of azobenzene groups. We show for the first time that merging of microdroplets can be achieved optically based on a photo-isomerization process with a high spatio-temporal resolution. Our results show that the physical process lying behind the merging of microdroplets is not driven by a change in surface activity of the droplet stabilizing surfactant under UV illumination (as originally expected), and they suggest an original mechanism for the merging of droplets based on the well-known opto-mechanical motion of azobenzene molecules triggered by light irradiation.
在这项工作中，我们报告了一种新合成的光活性可逆偶氮苯衍生表面活性剂聚合物的开发，该聚合物能够在脉冲紫外激光光学刺激和众所周知的偶氮苯基团光异构化的驱动下，对微流控腔中的微滴融合进行主动和快速控制。我们首次表明，基于光异构化过程，可以实现基于光异构化过程的微滴融合，具有高时空分辨率。我们的结果表明，微滴融合背后的物理过程不是由在 UV 照射下稳定表面活性剂的表面活性变化驱动的（最初预期的那样），并且它们基于光照射触发的偶氮苯分子的众所周知的光机械运动，提出了一种用于液滴融合的原始机制。
