Division of Pediatric Medicine and the Pediatric Outcomes Research Team (PORT), Hospital for Sick Children, Toronto, Ontario, Canada.
Department of Psychology, Hospital for Sick Children, Toronto, Ontario, Canada.
J Pediatr. 2020 Feb;217:189-191.e2. doi: 10.1016/j.jpeds.2019.09.051. Epub 2019 Nov 2.
In infants 1-3 years of age, we found higher serum ferritin values associated with higher cognitive function, as measured by the Mullen Scales of Early Learning (P = .02 for the nonlinear relationship). A serum ferritin of 17 μg/L corresponded to the maximum level of cognition, beyond which there was no meaningful improvement. TRIAL REGISTRATION: Clinicaltrials.gov NCT01481766 and NCT01869530.
在 1-3 岁的婴儿中,我们发现较高的血清铁蛋白值与较高的认知功能相关,这是通过 Mullen 早期学习量表来衡量的(非线性关系的 P 值为.02)。血清铁蛋白为 17μg/L 时,认知水平达到最高,之后再无显著改善。临床试验注册:Clinicaltrials.gov NCT01481766 和 NCT01869530。