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中国四川省藏区白内障的患病率及服务评估:基于人群的研究

Prevalence and service assessment of cataract in Tibetan areas of Sichuan Province, China: population-based study.

作者信息

Jiachu Danba, Jin Ling, Jiang Feng, Luo Li, Zheng Hong, Ji Duo, Yang Jing, Yongcuo Nima, Huang Wenyong, Yi Jinglin, Bright Tess, Yip Jennifer Ly, Xiao Baixiang

机构信息

Kham Eye Centre, Kandze Prefecture People's Hospital, Kangding, China.

Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

出版信息

BMJ Open. 2019 Nov 3;9(11):e031337. doi: 10.1136/bmjopen-2019-031337.

Abstract

OBJECTIVES

To assess the prevalence of visual impairment (VI) and blindness (BL) due to cataract and cataract surgical outcomes in remote dispersed and high-altitude Tibetan areas of China.

DESIGN AND SETTING

A cross-sectional study was conducted among people aged 50 and above in Tibetan Autonomous Prefecture of Kandze (TAPK), China, in 2017. The Rapid Assessment of Avoidable Blindness protocol was followed.

PARTICIPANTS

Of 5000 eligible participants, 4764 were examined (response rate 95.3%).

PRIMARY AND SECONDARY OUTCOME MEASURES

Cataract VI was defined as lens opacity at visual acuity (VA) levels of <3/60 (Blindness (BL)), ≥3/60 and <6/60 (severe visual impairment (SVI)), ≥6/60 and <6/18 (moderate visual impairment (MVI)), ≥6/18 and <6/12 (early visual impairment (EVI)).

RESULTS

The estimated prevalence of cataract BL was 0.61% (95% CI 0.42 to 0.87). With best corrected VA, the estimated prevalence of SVI from cataract was 0.86% (95% CI 0.63 to 1.17); MVI was 2.39% (95% CI 2.00 to 2.87) and EVI was 5.21% (95% CI 4.61 to 5.87). Women in TAPK had a significantly higher prevalence of cataract BL (0.82%, 95% CI 0.54 to 2.15) than men (0.34%, 95% CI 0.16 to 0.70). Women had lower cataract surgical coverage (CSC) by eyes (60.8%, 95% CI 55.5 to 65.8) compared with men (70.1%; 95% CI 63.7 to 75.7). The prevalence of cataract BL was higher among Tibetan (2.28%; 95% CI 1.98 to 2.62) than Han Chinese (1.01%%; 95% CI 0.54% to 1.87%). Overall CSC by person with BL (by better eye) was 82.0% (95% CI 75.2 to 87.6). Among cataract-operated participants, 71.2% had VA equal to or better than 6/18.

CONCLUSIONS

The study detected a low prevalence of VI and BL due to cataract with high CSC in the study area compared with many other places in China. Further actions should be taken to improve cataract surgical outcome.

摘要

目的

评估中国偏远分散且地处高海拔的藏族地区因白内障导致的视力损害(VI)和失明(BL)的患病率以及白内障手术效果。

设计与背景

2017年在中国甘孜藏族自治州(TAPK)对50岁及以上人群开展了一项横断面研究。遵循了可避免失明快速评估方案。

参与者

在5000名符合条件的参与者中,4764人接受了检查(应答率95.3%)。

主要和次要结局指标

白内障导致的视力损害定义为视力(VA)水平<3/60(失明(BL))、≥3/60且<6/60(严重视力损害(SVI))、≥6/60且<6/18(中度视力损害(MVI))、≥6/18且<6/12(早期视力损害(EVI))。

结果

白内障导致的失明估计患病率为0.61%(95%CI 0.42至0.87)。经最佳矫正视力后,白内障导致的严重视力损害估计患病率为0.86%(95%CI 0.63至1.17);中度视力损害为2.39%(95%CI 2.00至2.87),早期视力损害为5.21%(95%CI 4.61至5.87)。TAPK的女性白内障导致的失明患病率(0.82%,95%CI 0.54至2.15)显著高于男性(0.34%,95%CI 0.16至0.70)。与男性(70.1%;95%CI 63.7至75.7)相比,女性的白内障手术眼覆盖率(CSC)较低(60.8%,95%CI 55.5至65.8)。藏族人群中白内障导致的失明患病率(2.28%;95%CI 1.98至2.62)高于汉族人群(1.01%;95%CI 0.54%至1.87%)。失明者(较好眼)的总体CSC为82.0%(95%CI 75.2至87.6)。在接受白内障手术的参与者中,71.2%的人视力等于或优于6/18。

结论

与中国其他许多地方相比,该研究发现研究地区因白内障导致的视力损害和失明患病率较低,白内障手术覆盖率较高。应采取进一步行动以改善白内障手术效果。

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