文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

UCSC Genome Browser 迎来 20 周年。

UCSC Genome Browser enters 20th year.

机构信息

Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA.

Howard Hughes Medical Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA.

出版信息

Nucleic Acids Res. 2020 Jan 8;48(D1):D756-D761. doi: 10.1093/nar/gkz1012.


DOI:10.1093/nar/gkz1012
PMID:31691824
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7145642/
Abstract

The University of California Santa Cruz Genome Browser website (https://genome.ucsc.edu) enters its 20th year of providing high-quality genomics data visualization and genome annotations to the research community. In the past year, we have added a new option to our web BLAT tool that allows search against all genomes, a single-cell expression viewer (https://cells.ucsc.edu), a 'lollipop' plot display mode for high-density variation data, a RESTful API for data extraction and a custom-track backup feature. New datasets include Tabula Muris single-cell expression data, GeneHancer regulatory annotations, The Cancer Genome Atlas Pan-Cancer variants, Genome Reference Consortium Patch sequences, new ENCODE transcription factor binding site peaks and clusters, the Database of Genomic Variants Gold Standard Variants, Genomenon Mastermind variants and three new multi-species alignment tracks.

摘要

加州大学圣克鲁兹分校基因组浏览器网站(https://genome.ucsc.edu)迎来了向研究界提供高质量基因组数据可视化和基因组注释的第 20 个年头。在过去的一年里,我们在网络 BLAT 工具中添加了一个新选项,可以针对所有基因组进行搜索,单细胞表达查看器(https://cells.ucsc.edu),高密度变异数据的棒棒糖图显示模式,用于数据提取的 RESTful API 和自定义轨道备份功能。新数据集包括 Tabula Muris 单细胞表达数据、GeneHancer 调控注释、癌症基因组图谱泛癌变体、基因组参考联盟补丁序列、新的 ENCODE 转录因子结合位点峰和簇、基因组变异数据库金标准变异、Genomenon Mastermind 变异以及三个新的多物种对齐轨道。

相似文献

[1]
UCSC Genome Browser enters 20th year.

Nucleic Acids Res. 2020-1-8

[2]
The UCSC Genome Browser database: 2014 update.

Nucleic Acids Res. 2013-11-21

[3]
The UCSC Genome Browser database: update 2010.

Nucleic Acids Res. 2009-11-11

[4]
The UCSC Genome Browser database: extensions and updates 2013.

Nucleic Acids Res. 2012-11-15

[5]
The UCSC Genome Browser Database.

Nucleic Acids Res. 2003-1-1

[6]
Track data hubs enable visualization of user-defined genome-wide annotations on the UCSC Genome Browser.

Bioinformatics. 2013-11-13

[7]
ENCODE whole-genome data in the UCSC Genome Browser.

Nucleic Acids Res. 2009-11-17

[8]
The UCSC Genome Browser database: 2023 update.

Nucleic Acids Res. 2023-1-6

[9]
The UCSC genome browser and associated tools.

Brief Bioinform. 2012-8-20

[10]
The UCSC Genome Browser database: 2019 update.

Nucleic Acids Res. 2019-1-8

引用本文的文献

[1]
Exploration of Comprehensive Structural and Functional Potential of Recombinant Proteins Using Cutting-Edge Bioinformatics Tools.

Appl Biochem Biotechnol. 2025-9-9

[2]
Genome-wide identification of the H3K27ac signals reveals key thermogenic cis-regulatory elements of brown adipose tissues in Oryctolagus cuniculus.

BMC Genomics. 2025-7-25

[3]
A Vision for VenomsBase: An Integrated Knowledgebase for the Study of Venoms and Their Applications.

Integr Org Biol. 2025-6-27

[4]
Genetically encoded affinity reagents are a toolkit for visualizing and manipulating endogenous protein function in vivo.

Nat Commun. 2025-7-1

[5]
GNG7 as a tumor-suppressor gene in lung adenocarcinoma: implications for prognosis and immune-based therapies.

Front Oncol. 2025-5-27

[6]
TFEBexplorer: An integrated tool to study genes regulated by the stress-responsive Transcription Factor EB.

Autophagy Rep. 2022-7-21

[7]
Integrative analysis of m6A-SNPs and single-cell RNA sequencing reveals key drivers of endocrine combined with CDK4/6 inhibitor therapy resistance in ER+ breast cancer.

Front Pharmacol. 2025-4-15

[8]
Pan-cancer analysis of DLAT reveals it as a prognostic Biomarker involved in immune infiltration of liver hepatocellular carcinoma.

J Cancer. 2025-3-21

[9]
Multi-Omics Characterization of Genome-Wide Abnormal DNA Methylation Reveals FGF5 as a Diagnosis of Nasopharyngeal Carcinoma Recurrence After Radiotherapy.

Biomolecules. 2025-2-14

[10]
Heterozygous UBR5 variants result in a neurodevelopmental syndrome with developmental delay, autism, and intellectual disability.

Am J Hum Genet. 2025-1-2

本文引用的文献

[1]
DASHR 2.0: integrated database of human small non-coding RNA genes and mature products.

Bioinformatics. 2019-3-15

[2]
Structurally Conserved Primate LncRNAs Are Transiently Expressed during Human Cortical Differentiation and Influence Cell-Type-Specific Genes.

Stem Cell Reports. 2019-1-10

[3]
A map of direct TF-DNA interactions in the human genome.

Nucleic Acids Res. 2019-2-28

[4]
The UCSC Genome Browser database: 2019 update.

Nucleic Acids Res. 2019-1-8

[5]
Revealing a human p53 universe.

Nucleic Acids Res. 2018-9-19

[6]
Integrating single-cell transcriptomic data across different conditions, technologies, and species.

Nat Biotechnol. 2018-4-2

[7]
SCANPY: large-scale single-cell gene expression data analysis.

Genome Biol. 2018-2-6

[8]
GeneHancer: genome-wide integration of enhancers and target genes in GeneCards.

Database (Oxford). 2017-1-1

[9]
The Human Gene Mutation Database: towards a comprehensive repository of inherited mutation data for medical research, genetic diagnosis and next-generation sequencing studies.

Hum Genet. 2017-6

[10]
Toward a Shared Vision for Cancer Genomic Data.

N Engl J Med. 2016-9-22

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索