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质子治疗的实施:未来十年需要什么?

Proton therapy delivery: what is needed in the next ten years?

机构信息

Provision Center for Proton therapy - Knoxville, 6450 Provision Cares way, Knoxville, TN 37909, USA.

ProNova Solutions, LLC, 330 Pellissippi Place, Maryville, TN 37804, USA.

出版信息

Br J Radiol. 2020 Mar;93(1107):20190359. doi: 10.1259/bjr.20190359. Epub 2019 Nov 14.

Abstract

Proton radiation therapy has been used clinically since 1952, and major advancements in the last 10 years have helped establish protons as a major clinical modality in the cancer-fighting arsenal. Technologies will always evolve, but enough major breakthroughs have been accomplished over the past 10 years to allow for a major revolution in proton therapy. This paper summarizes the major technology advancements with respect to beam delivery that are now ready for mass implementation in the proton therapy space and encourages vendors to bring these to market to benefit the cancer population worldwide. We state why these technologies are essential and ready for implementation, and we discuss how future systems should be designed to accommodate their required features.

摘要

质子放射治疗自 1952 年以来就已应用于临床,过去 10 年的重大进展帮助确立了质子治疗在癌症治疗中的主要临床地位。技术总是在不断发展,但在过去的 10 年中已经取得了足够多的重大突破,使得质子治疗发生了重大变革。本文总结了在束流传输方面的重大技术进步,这些进步现在已经准备好在质子治疗领域大规模应用,并鼓励供应商将这些技术推向市场,使全球癌症患者受益。我们陈述了这些技术的重要性和实施的准备情况,并讨论了未来的系统应该如何设计以适应它们所需的功能。

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本文引用的文献

1
Validation of the RayStation Monte Carlo dose calculation algorithm using realistic animal tissue phantoms.
J Appl Clin Med Phys. 2019 Oct;20(10):160-171. doi: 10.1002/acm2.12733. Epub 2019 Sep 21.
2
AlignRT and Catalyst™ in whole-breast radiotherapy with DIBH: Is IGRT still needed?
J Appl Clin Med Phys. 2019 Mar;20(3):97-104. doi: 10.1002/acm2.12553.
3
Biological effects in normal cells exposed to FLASH dose rate protons.
Radiother Oncol. 2019 Oct;139:51-55. doi: 10.1016/j.radonc.2019.02.009. Epub 2019 Mar 5.
4
Contour scanning, multi-leaf collimation and the combination thereof for proton pencil beam scanning.
Phys Med Biol. 2018 Dec 20;64(1):015002. doi: 10.1088/1361-6560/aaf2e8.
6
New horizons in particle therapy systems.
Med Phys. 2018 Nov;45(11):e953-e983. doi: 10.1002/mp.13193.
7
In vivo range verification in particle therapy.
Med Phys. 2018 Nov;45(11):e1036-e1050. doi: 10.1002/mp.12960.
8
Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods.
Int J Cancer. 2019 Apr 15;144(8):1941-1953. doi: 10.1002/ijc.31937. Epub 2018 Dec 6.
9
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
CA Cancer J Clin. 2018 Nov;68(6):394-424. doi: 10.3322/caac.21492. Epub 2018 Sep 12.
10
A full-scale clinical prototype for proton range verification using prompt gamma-ray spectroscopy.
Phys Med Biol. 2018 Sep 17;63(18):185019. doi: 10.1088/1361-6560/aad513.

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