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白色念珠菌:食管壁内假性憩室病的病因还是后果?

Candida albicans: a cause or a consequence of esophageal intramural pseudo-diverticulosis.

作者信息

Akkari Imen, Jazia Elhem Ben, Mrabet Soumaya, Jemni Imen

机构信息

Gastroenterology Department, Farhat Hached Hospital, Sousse, Tunisia.

出版信息

Pan Afr Med J. 2019 Aug 2;33:280. doi: 10.11604/pamj.2019.33.280.19601. eCollection 2019.

Abstract

Esophageal intramural pseudo-diverticulosis is a rare disease of unknown etiology. It is characterized by multiple pseudodiverticula with segmental or diffuse involvement of the esophagus. We report, the case of a 78-year-old male who suffered from severe dysphagia. Diagnosis of esophageal intramural pseudo-diverticulosis was based on endoscopic and radiologic explorations. Histological analysis of esophageal mucosal biopsies has shown the presence of candida albicans. Antifungal treatment leads to spectacular improvement of dysphasia. Subsequently, the patient presented a cardio-respiratory failure and died despite adequate treatment.

摘要

食管壁内假性憩室病是一种病因不明的罕见疾病。其特征为多个假性憩室,食管呈节段性或弥漫性受累。我们报告一例78岁男性患者,该患者患有严重吞咽困难。食管壁内假性憩室病的诊断基于内镜检查和影像学检查。食管黏膜活检的组织学分析显示存在白色念珠菌。抗真菌治疗使吞咽困难症状显著改善。随后,患者出现心肺衰竭,尽管接受了适当治疗仍死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d82/6815468/4506073bee29/PAMJ-33-280-g001.jpg

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