Ontogeny of mitogen responsive lymphocytes in the bovine fetus.
作者信息
Jensen J, Rubino M, Yang W C, Cooley A J, Schultz R D
机构信息
Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706.
出版信息
Dev Comp Immunol. 1988 Summer;12(3):685-92. doi: 10.1016/0145-305x(88)90083-3.
PMID:3169358
Abstract
Bovine fetal lymphocytes were examined for their ability to respond to the mitogens phytohemagglutinin (PHA), Concanavalin A (ConA) and pokeweed mitogen (PWM) in the lymphocyte blastogenesis test (LBT). PHA-, Con A- and PWM-responsive lymphocytes appeared simultaneously at 75-80 days of gestation. The response increased with age of the fetus until, by 120 days of gestation, the response to PHA, Con A and PWM of many fetuses was in the range of values obtained with lymphocytes from normal adult cattle.
摘要
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