六种韩国植物对胰高血糖素样肽-1释放的影响。
Effect of six Korean plants on glucagon like peptide-1 release.
作者信息
Cho Hyunnho, Kim Kyong, Jang Dae-Ja, Kim Hye Young
机构信息
Division of Food Function Research, Korea Food Research Institute, 245 Nongsaengmyeong-ro, Iseo-myeon, Wanju-gun, Jeollabuk-do 55365 Republic of Korea.
出版信息
Food Sci Biotechnol. 2019 Mar 26;28(5):1571-1576. doi: 10.1007/s10068-019-00603-x. eCollection 2019 Oct.
Glucagon like peptide-1 (GLP-1) plays a major role in the regulation of energy homeostasis as it causes satiety and suppresses appetite. , , , , and have traditionally been used as famine relief foods in Korea. The aim of the present study was to determine whether the aqueous ethanolic extracts of the six plants stimulate GLP-1 secretion. The results demonstrated that each extract of the plants stimulated GLP-1 secretion from enteroendocrine NCI-H716 cells, respectively. Among the extracts examined, the extract of showed the highest activity on GLP-1 release. The results may suggest that the GLP-1 secretion induced by the six plants is a possible mechanism for the six plants exerting effects on satiety increase and appetite suppression.
胰高血糖素样肽-1（GLP-1）在能量平衡调节中起主要作用，因为它会引起饱腹感并抑制食欲。在韩国，传统上一直将[此处原文缺失具体植物名称]用作救灾食品。本研究的目的是确定这六种植物的乙醇水提取物是否能刺激GLP-1分泌。结果表明，每种植物提取物分别刺激肠内分泌NCI-H716细胞分泌GLP-1。在所检测的提取物中，[此处原文缺失具体植物名称]提取物对GLP-1释放的活性最高。这些结果可能表明，这六种植物诱导的GLP-1分泌是它们对增加饱腹感和抑制食欲发挥作用的一种可能机制。
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