通过原位杂交对马的主要组织相容性复合体（ELA）进行染色体定位。
Chromosomal localization of the major histocompatibility complex of the horse (ELA) by in situ hybridization.
作者信息
Ansari H A, Hediger R, Fries R, Stranzinger G
机构信息
Swiss Federal Institute of Technology, Institute of Animal Sciences, Zurich, Switzerland.
出版信息
Immunogenetics. 1988;28(5):362-4. doi: 10.1007/BF00364235.
PMID:3169882
Abstract
The first gene assignment to a horse chromosome is reported for equine leucocyte antigen (ELA), the major histocompatibility complex of the horse. A cloned DNA sequence derived from a class I gene of the porcine major histocompatibility complex was used as a probe for an in situ hybridization experiment. We present the regional localization of ELA, using this sequence, to equine chromosome 20q14-q22.
摘要
报道了马主要组织相容性复合体——马白细胞抗原（ELA）的首个基因定位到马染色体上的情况。一个源自猪主要组织相容性复合体I类基因的克隆DNA序列被用作原位杂交实验的探针。我们利用该序列将ELA定位到马的20号染色体q14 - q22区域。
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