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一名青少年患者的颈椎C4骨母细胞瘤伴继发性动脉瘤样骨囊肿:2年随访

C4 cervical spine osteoblastoma associated with secondary aneurysmal bone cyst in an adolescent patient: 2-year follow-up.

作者信息

Gahlot Nitesh, Jalan Divesh, Elhence Poonam

机构信息

1Department of Orthopedics, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan India.

2Department of Orthopedics, Safdurjung and VMMC, New Delhi, India.

出版信息

Spinal Cord Ser Cases. 2019 Oct 22;5:89. doi: 10.1038/s41394-019-0233-5. eCollection 2019.

Abstract

INTRODUCTION

Osteoblastoma and aneurysmal bone cyst (ABC) are rare bone tumors with individual prevalence of <1%. Their combined occurrence is a rare subclass of tumors in the spinal column with only a few cases reported in literature.

CASE PRESENTATION

The present case is a rare combination of aggressive osteoblastoma with secondary aneurysmal bone cyst masquerading as neck pain, arising from cervical C4 vertebra in a 19-year-old male. The patient presented with complaints of neck pain for 7 months, gradual in onset, dull, aching, and progressively increasing in severity. Neurological examination was normal. Radiology showed an expansile lytic mass arising from the posterior elements of C4 vertebra involving the left lateral mass. Piecemeal total removal was done and a posterior fusion from C3 to C5 was performed for stability. Histopathology confirmed the osteoblastoma with a secondary aneurysmal bone cyst. Postoperatively the patient recovered well, and no recurrence was seen on a 2-year follow-up.

DISCUSSION

Simultaneous presence of an osteoblastoma with a secondary ABC arising from various bones, such as cranial fossa, ethmoid sinus, skull, and mandibular condyle, has rarely been reported. It is often diagnosed late due to nonspecific symptoms; but it has a good prognosis if early and complete resection is performed. Thorough surgical excision is always a challenge in spine cases due to surrounding important structures and meticulousness is required to prevent any recurrences. Hence, we recommend a surgical team comprising both spine and musculoskeletal oncologic surgeons to achieve best results.

摘要

引言

骨母细胞瘤和骨动脉瘤样囊肿(ABC)是罕见的骨肿瘤,个体患病率<1%。它们同时出现是脊柱肿瘤中一种罕见的亚类,文献中仅报道了少数病例。

病例报告

本病例是一例罕见的侵袭性骨母细胞瘤合并继发性骨动脉瘤样囊肿,表现为颈部疼痛,发生于一名19岁男性的颈椎C4椎体。患者主诉颈部疼痛7个月,起病缓慢,钝痛,呈进行性加重。神经系统检查正常。影像学检查显示C4椎体后部出现一个膨胀性溶骨性肿块,累及左侧块。进行了分块全切,并进行了C3至C5的后路融合以保持稳定。组织病理学证实为骨母细胞瘤合并继发性骨动脉瘤样囊肿。术后患者恢复良好,2年随访未见复发。

讨论

骨母细胞瘤与起源于颅窝、筛窦、颅骨和下颌髁等不同骨骼的继发性ABC同时存在的情况鲜有报道。由于症状不具特异性,该病常被误诊;但如果早期进行彻底切除,预后良好。由于脊柱周围有重要结构,彻底的手术切除在脊柱病例中始终是一项挑战,需要谨慎操作以防止复发。因此,我们建议由脊柱和肌肉骨骼肿瘤外科医生组成的手术团队来取得最佳治疗效果。

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