Department of Plant and Soil Sciences, University of Kentucky, Lexington, Kentucky.
Wiley Interdiscip Rev RNA. 2020 May;11(3):e1575. doi: 10.1002/wrna.1575. Epub 2019 Nov 7.
3' end processing and mRNA polyadenylation is a vital aspect of gene expression in eukaryotes, and also a step at which expression may be regulated. A spate of recent research in plants links different subunits of the polyadenylation complex with growth and development. These reports provide insight into mechanisms by which APA may be regulated, and perhaps into mechanisms by which pre-mRNAs are processed and polyadenylated. In this review, several of these recent reports are discussed, with the purpose of highlighting novel features of mRNA 3' end formation in plants and also developing broad themes that connect APA with plant growth, development, and responses to the environment. This article is categorized under: RNA Processing > 3' End Processing RNA in Disease and Development > RNA in Development.
3' 端加工和 mRNA 多聚腺苷酸化是真核生物基因表达的一个重要方面,也是表达可能受到调控的一个步骤。最近在植物中进行的大量研究将多聚腺苷酸化复合物的不同亚基与生长和发育联系起来。这些报告提供了对 APA 可能受到调控的机制的深入了解,也许还提供了对前体 mRNA 加工和多聚腺苷酸化的机制的了解。在这篇综述中,讨论了其中的一些最新报告,目的是突出植物中 mRNA 3' 端形成的新特征,并形成将 APA 与植物生长、发育和对环境的反应联系起来的广泛主题。本文属于以下分类:RNA 加工 > 3' 端加工 RNA 在疾病与发育中的作用 > RNA 在发育中的作用。