Datar Praveen, Sidhu Jasdeep Singh, Virk Jeevanjot, Mukhtar Osama, Schmidt Frances, Gayam Vijay
Interfaith Medical Center, Brooklyn, NY, USA.
J Investig Med High Impact Case Rep. 2019 Jan-Dec;7:2324709619883466. doi: 10.1177/2324709619883466.
Hemodialysis machines are equipped with a blood leak detector/alarm to prevent loss of blood following rupture of semipermeable membrane; the blood leak alarms could also be triggered by sensor malfunction or presence of air bubbles in the system. Hydroxocobalamin is a Food and Drug Administration-approved rapid-acting antidote to cyanide poisoning that converts cyanide to nontoxic cyanocobalamin. Side effects are reddish discoloration of skin and body fluids, urticarial rash, and rarely anaphylaxis. In this article, a case of false blood leak alarm following treatment of cyanide poisoning with hydroxocobalamin is reported, wherein the blood leak detector in dialysis machines prevented the patient from undergoing hemodialysis by repeatedly activating blood leak alarms. Continuous renal replacement therapy was used to overcome this problem. As the use of hydroxocobalamin increases, health care professionals should be educated about its potential to interfere with hemodialysis.
血液透析机配备有血液泄漏探测器/警报器，以防止半透膜破裂后血液流失；血液泄漏警报也可能由传感器故障或系统中存在气泡触发。羟钴胺素是一种经美国食品药品监督管理局批准的用于氰化物中毒的速效解毒剂，它可将氰化物转化为无毒的氰钴胺素。其副作用包括皮肤和体液发红、荨麻疹皮疹，很少会出现过敏反应。本文报告了一例在用羟钴胺素治疗氰化物中毒后出现假性血液泄漏警报的病例，其中透析机中的血液泄漏探测器通过反复触发血液泄漏警报，阻止了患者进行血液透析。采用持续肾脏替代疗法来解决这一问题。随着羟钴胺素使用的增加，应让医护人员了解其干扰血液透析的可能性。
