Araji Ghada, Keesari Praneeth R, Chowdhry Varun, Valsechi-Diaz Jonathan, Afif Sarah, Diab Wassim, El-Sayegh Suzanne
Department of Internal Medicine, Northwell Health-Staten Island University Hospital, Staten Island, NY 10305, United States.
Department of Internal Medicine, CUNY School of Medicine, New York, NY 10031, United States.
World J Nephrol. 2024 Dec 25;13(4):100268. doi: 10.5527/wjn.v13.i4.100268.
Vitamin B12 deficiency is a significant concern among patients with end-stage renal disease undergoing dialysis. However, there hasn't been extensive research conducted on this particular patient group. The reported incidence rates vary widely, ranging from 20% to 90%, reflecting the complexity of its diagnosis. Dialysis patients often face multiple nutritional deficiencies, including a lack of essential vitamins, due to factors such as dietary restrictions, impaired absorption, and nutrient loss during dialysis. Diagnosing vitamin B12 deficiency in these patients is challenging, and addressing it is crucial to prevent complications and improve their overall quality of life. This review paper delves into the available body of evidence on vitamin B12 deficiency in dialysis patients, examining the contributing risk factors, diagnostic challenges, potential complications, and available treatment options. It provides a well-rounded perspective on the topic, making it a valuable resource for researchers, healthcare practitioners, and policymakers interested in addressing the nutritional needs of dialysis patients.
维生素B12缺乏是接受透析的终末期肾病患者的一个重大问题。然而，针对这一特定患者群体尚未进行广泛研究。报道的发病率差异很大，从20%到90%不等，这反映了其诊断的复杂性。由于饮食限制、吸收受损以及透析过程中的营养流失等因素，透析患者常常面临多种营养缺乏，包括必需维生素的缺乏。诊断这些患者的维生素B12缺乏具有挑战性，而解决这一问题对于预防并发症和提高他们的整体生活质量至关重要。这篇综述论文深入探讨了关于透析患者维生素B12缺乏的现有证据，研究了相关危险因素、诊断挑战、潜在并发症以及可用的治疗选择。它提供了关于该主题的全面观点，对于有兴趣满足透析患者营养需求的研究人员、医疗从业者和政策制定者而言，是一份有价值的资源。
