Thylefors B, Duppenthaler J L
Bull World Health Organ. 1979;57(6):963-9.
A field investigation of intraocular pressure in populations in onchocerciasis endemic areas of West Africa revealed a normal pressure distribution in individuals without signs of ocular onchocerciasis or with only microfilariae or reversible lesions in the eye. Females showed a significantly higher mean ocular tension, and in both sexes tension decreased with age. Patients with irreversible onchocercal ocular lesions and signs of anterior uveitis showed a significantly lower and abnormally distributed intraocular pressure. The prevalence of glaucoma was significantly higher in this group, thus indicating that a high intensity of onchocercal infection may be associated with a risk of secondary glaucoma. The presence of microfilariae in the ocular tissues and consequent inflammatory reactions may possibly give rise to an abnormal distribution of ocular tension.
对西非盘尾丝虫病流行地区人群眼压的一项现场调查显示，在没有眼部盘尾丝虫病体征、或仅眼部有微丝蚴或可逆性病变的个体中，眼压分布正常。女性的平均眼压显著较高，且两性的眼压均随年龄增长而降低。患有不可逆性盘尾丝虫性眼部病变和前葡萄膜炎体征的患者眼压显著较低且分布异常。该组青光眼患病率显著较高，因此表明高强度的盘尾丝虫感染可能与继发性青光眼风险相关。眼部组织中微丝蚴的存在及随之发生的炎症反应可能会导致眼压分布异常。
